{"id":"W3015939137","doi":"10.1210/endocr/bqaa056","title":"Murine FSH Production Depends on the Activin Type II Receptors ACVR2A and ACVR2B","year":2020,"lang":"en","type":"article","venue":"Endocrinology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute on Aging; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Institut de Recherche Clinique De Montréal","keywords":"ACVR2B; Activin receptor; Endocrinology; Internal medicine; Gonadotropic cell; Activin type 2 receptors; Biology; Receptor; Luteinizing hormone; TGF beta signaling pathway; Hormone; Transforming growth factor; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001534794,0.0004876426,0.0002210892,0.0006905856,0.0002390891,0.0004860953,0.0003289898,0.0003570004,0.004244583],"category_scores_gemma":[0.0001245675,0.0004669736,0.0004172165,0.0002255148,0.0003368422,0.0002244996,0.0003449259,0.0007590852,0.002104708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003112526,"about_ca_system_score_gemma":0.0002322057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001277619,"about_ca_topic_score_gemma":0.001788428,"domain_scores_codex":[0.9996544,0.00002839675,0.00004107905,0.00009655736,0.0001018549,0.00007768049],"domain_scores_gemma":[0.9996847,0.00002788638,0.0001033626,0.00003860771,0.00002464078,0.0001208684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008254096,0.000008825562,0.0002309461,0.0000120308,0.000002424589,0.00003271763,0.0000122385,0.00002166142,0.9989355,0.00007253505,0.00003699767,0.0005515953],"study_design_scores_gemma":[0.00007214815,0.0003534495,0.01622283,0.00002648682,0.00003045668,0.0007309513,0.00007760952,0.0006612389,0.972909,0.00007186797,0.008829989,0.00001404967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844534,0.00180474,0.003855432,0.0002118767,0.00006607945,0.00005309987,0.003150151,0.0001989936,0.006206305],"genre_scores_gemma":[0.9730162,0.001400048,0.003867793,0.0001253923,0.0000242875,0.00009516951,0.002857018,0.0001618568,0.01845231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004244583,"threshold_uncertainty_score":0.01419961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02252331839911047,"score_gpt":0.2459563440255335,"score_spread":0.2234330256264231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}