{"id":"W3015941631","doi":"10.1002/mus.26887","title":"Guidelines on clinical presentation and management of nondystrophic myotonias","year":2020,"lang":"en","type":"review","venue":"Muscle & Nerve","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Wellcome Trust; Advanced Foods and Materials Canada","keywords":"Mexiletine; Myotonia; Myotonia congenita; Medicine; Channelopathy; Weakness; Muscle relaxation; Muscle weakness; Anesthesia; Internal medicine; Surgery; Myotonic dystrophy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008192003,0.001119406,0.001455814,0.002892789,0.0004044146,0.0008909001,0.001846075,0.002134263,0.01307267],"category_scores_gemma":[0.002364328,0.0002661871,0.001037019,0.001584117,0.0003622551,0.001047642,0.0007496582,0.001999009,0.01189661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006791258,"about_ca_system_score_gemma":0.001404498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002515035,"about_ca_topic_score_gemma":0.004854348,"domain_scores_codex":[0.9995131,0.000118677,0.0001412834,0.00004393411,0.0001358951,0.00004695985],"domain_scores_gemma":[0.9990861,0.0003392623,0.0001368136,0.00002040392,0.0003477235,0.00006952178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007649061,0.00009512895,0.0003687424,0.00854516,0.00005592779,0.00162565,0.0001228671,0.0004245965,0.001098528,0.004022616,0.3983452,0.5852191],"study_design_scores_gemma":[0.00005610139,0.000046808,0.001068918,0.01276645,0.00006815208,0.007190446,0.0000862419,0.0001010375,0.0001979151,0.003037952,0.9753524,0.0000275525],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008330719,0.9459161,0.003776283,0.009335788,0.003307909,0.0003668263,0.001761483,0.0003741291,0.03432846],"genre_scores_gemma":[0.005435677,0.9465662,0.01151578,0.009291825,0.002248114,0.0006401797,0.005848249,0.00008871336,0.01836527],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01307267,"threshold_uncertainty_score":0.04373246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3165302670412412,"score_gpt":0.4606781117328295,"score_spread":0.1441478446915883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}