{"id":"W3016119892","doi":"10.1002/hep4.1516","title":"Hepatic Choline Transport Is Inhibited During Fatty Acid–Induced Lipotoxicity and Obesity","year":2020,"lang":"en","type":"article","venue":"Hepatology Communications","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Texas Health Science Center at San Antonio; Ontario Ministry of Research, Innovation and Science; Ministry of Education, Culture, Sports, Science and Technology; National Institute on Aging; University of Alberta; Canadian Institutes of Health Research; University of Texas System","keywords":"Choline; Endocrinology; Internal medicine; Lipotoxicity; Lipogenesis; Chemistry; Biology; Phosphatidylcholine; Fatty liver; Steatosis; Lipid metabolism; Biochemistry; Phospholipid; Obesity; Medicine; Insulin resistance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000167526,0.0003450521,0.0005271567,0.0003501042,0.0001616492,0.000426714,0.0001818058,0.0002815389,0.001295937],"category_scores_gemma":[0.0002477959,0.000284845,0.000361508,0.0002536035,0.0003434483,0.0002543845,0.0002832386,0.0006649813,0.0004783661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003954157,"about_ca_system_score_gemma":0.0003054039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001168259,"about_ca_topic_score_gemma":0.001759032,"domain_scores_codex":[0.9998216,0.00002663358,0.00002056318,0.00003925422,0.00003486591,0.00005698821],"domain_scores_gemma":[0.9997484,0.00002504178,0.00007496407,0.00003743918,0.00004457424,0.00006960503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001213806,0.00002760814,0.0003749349,0.00004327068,0.00001032607,0.0000572791,0.00002190302,0.00002105649,0.9974127,0.00003679325,0.00003319973,0.0007470492],"study_design_scores_gemma":[0.00007159177,0.0007020301,0.02154925,0.00001567697,0.00004220138,0.00030415,0.0001208385,0.0007890985,0.9741164,0.00008950885,0.002187218,0.00001204422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955003,0.001794996,0.001312685,0.0001672699,0.00004841853,0.00002468615,0.0003426926,0.0000847314,0.0007242862],"genre_scores_gemma":[0.9934763,0.0009399999,0.0008433758,0.0001128718,0.00001439748,0.0000587943,0.000989244,0.00005169608,0.003513284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001295937,"threshold_uncertainty_score":0.004335284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05259807971612568,"score_gpt":0.2939634290524766,"score_spread":0.2413653493363509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}