{"id":"W3016263801","doi":"10.1101/2020.04.07.030650","title":"The spatial and cell-type distribution of SARS-CoV-2 receptor ACE2 in human and mouse brain","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Long-Term Effects of COVID-19","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Zhejiang Chinese Medical University; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Olfactory bulb; Biology; Human brain; Hippocampal formation; Hippocampus; Neuroscience; Cell type; Angiotensin-converting enzyme 2; Choroid plexus; Central nervous system; Cell; Pathology; Coronavirus disease 2019 (COVID-19); Medicine; Disease; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001476172,0.0002359929,0.0002441094,0.0007808059,0.0001681715,0.0003282593,0.0001193609,0.0002389751,0.001926667],"category_scores_gemma":[0.0001385311,0.0001530597,0.000363034,0.0003809762,0.0001576312,0.0002293337,0.000168775,0.0002829803,0.0005974373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001770768,"about_ca_system_score_gemma":0.0001543884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001274369,"about_ca_topic_score_gemma":0.001525392,"domain_scores_codex":[0.9998139,0.00001384452,0.00001229777,0.00007891155,0.00004091629,0.00004029251],"domain_scores_gemma":[0.9999409,0.000006935412,0.00001912089,0.000008045157,0.00001321139,0.00001181568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000560677,0.00003246721,0.007386091,0.0001461176,0.00008063056,0.0001633092,0.00006615067,0.0001772233,0.9848906,0.0002004426,0.0005013315,0.005794985],"study_design_scores_gemma":[0.00007423825,0.0004812858,0.4215464,0.0000807863,0.0003000425,0.004050713,0.0005301611,0.005165627,0.5475684,0.0009764854,0.01916612,0.00005970362],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9728678,0.004869158,0.008033043,0.0001485713,0.00004903081,0.00002852759,0.01111707,0.0002136706,0.00267307],"genre_scores_gemma":[0.980965,0.002189773,0.004695414,0.0001736931,0.00001890321,0.00007275812,0.009501696,0.00007294709,0.002309838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001926667,"threshold_uncertainty_score":0.006445348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0176609400284353,"score_gpt":0.2685096965620769,"score_spread":0.2508487565336416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}