{"id":"W3016290335","doi":"10.1038/s41379-020-0535-y","title":"High-grade transformation of low-grade endometrial stromal sarcomas lacking YWHAE and BCOR genetic abnormalities","year":2020,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Uterine Myomas and Treatments","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Spinal Cord Injury BC; University of British Columbia; University of Toronto; Vancouver General Hospital; Mount Sinai Hospital","funders":"National Cancer Institute; Memorial Sloan-Kettering Cancer Center","keywords":"Endometrial stromal sarcoma; Fluorescence in situ hybridization; Pathology; Hematopathology; Population; Stromal cell; Medicine; Fusion gene; Sarcoma; Biology; Cytogenetics; Chromosome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006015929,0.0001475717,0.0004170845,0.0001160038,0.00003422029,0.000009394202,0.00005360288,0.00009471965,0.0000270045],"category_scores_gemma":[0.00002859882,0.0001320127,0.00007505086,0.000101268,0.00009499575,0.00007931059,0.00003627082,0.0001094121,0.0000049201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001806241,"about_ca_system_score_gemma":0.00002507853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004507742,"about_ca_topic_score_gemma":0.000006759718,"domain_scores_codex":[0.9990061,0.00006450886,0.0003314293,0.0002202091,0.0001536351,0.0002241304],"domain_scores_gemma":[0.9995974,0.00004537761,0.00008561298,0.0001333349,0.00002516226,0.0001131469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004542477,0.001699632,0.2934681,0.002487993,0.001038584,0.006517426,0.05027662,0.0004840789,0.4888966,0.00615874,0.0001164761,0.1443132],"study_design_scores_gemma":[0.03844436,0.007396118,0.866459,0.0001483049,0.0008197868,0.002337524,0.0006054247,0.01204849,0.06779581,0.002491908,0.0008593982,0.0005939418],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934638,0.0006595654,0.004338686,0.0009471239,0.0001049343,0.0003053372,0.00006046494,0.00004618287,0.00007395451],"genre_scores_gemma":[0.9960631,0.0001393936,0.0032925,0.0002402968,0.0001488584,0.00001762514,0.00006058357,0.00001965935,0.00001805024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5729908,"threshold_uncertainty_score":0.5383322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03074148063206304,"score_gpt":0.2617418576167103,"score_spread":0.2310003769846473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}