{"id":"W3016305930","doi":"10.1182/blood.v130.suppl_1.98.98","title":"CA180-372: An International Collaborative Phase 2 Trial of Dasatinib and Chemotherapy in Pediatric Patients with Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Dasatinib; Medicine; Internal medicine; Imatinib; Oncology; Minimal residual disease; Chemotherapy; Philadelphia chromosome; Imatinib mesylate; Acute lymphocytic leukemia; Clinical trial; Hematopoietic stem cell transplantation; Chemotherapy regimen; Leukemia; Transplantation; Lymphoblastic Leukemia; Chromosomal translocation; Myeloid leukemia; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002279823,0.001804085,0.001719838,0.0004879539,0.0005167385,0.0009340362,0.001267608,0.001177435,0.003879524],"category_scores_gemma":[0.001020796,0.000660761,0.001047162,0.0006077443,0.001118278,0.001027285,0.0007188079,0.004016797,0.0007817586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001424122,"about_ca_system_score_gemma":0.002545724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001564096,"about_ca_topic_score_gemma":0.004479251,"domain_scores_codex":[0.9991979,0.0003868421,0.00004953364,0.0001495192,0.00008831691,0.0001279362],"domain_scores_gemma":[0.9992324,0.00009324249,0.0001353405,0.00005897466,0.00004045341,0.0004395215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7175993,0.09317681,0.01096742,0.001850873,0.002688483,0.0006361073,0.0008600185,0.004259325,0.03270453,0.001143186,0.01276327,0.1213506],"study_design_scores_gemma":[0.8179843,0.1680382,0.006225427,0.00003377169,0.0004443841,0.0004469052,0.00006558836,0.0006149115,0.001893701,0.0002772879,0.003945971,0.00002946246],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853013,0.002887971,0.0005477882,0.001278316,0.0001738791,0.004957941,0.001750805,0.0001050122,0.002997011],"genre_scores_gemma":[0.9780753,0.002785149,0.00348969,0.001779268,0.000201172,0.006616618,0.003926485,0.00004446302,0.003081992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003879524,"threshold_uncertainty_score":0.01297826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01066105177175042,"score_gpt":0.2896659076061985,"score_spread":0.2790048558344481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}