{"id":"W3016305930","doi":"10.1182/blood.v130.suppl_1.98.98","title":"CA180-372: An International Collaborative Phase 2 Trial of Dasatinib and Chemotherapy in Pediatric Patients with Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Dasatinib; Medicine; Internal medicine; Imatinib; Oncology; Minimal residual disease; Chemotherapy; Philadelphia chromosome; Imatinib mesylate; Acute lymphocytic leukemia; Clinical trial; Hematopoietic stem cell transplantation; Chemotherapy regimen; Leukemia; Transplantation; Lymphoblastic Leukemia; Chromosomal translocation; Myeloid leukemia; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001057346,0.0003043001,0.0005485637,0.0001927543,0.00009566252,0.00005649248,0.0002427955,0.0001389419,0.00005931449],"category_scores_gemma":[0.0001877938,0.0002513853,0.00004977289,0.0001574552,0.0001683871,0.0004004449,0.00006494934,0.0001555036,0.000003938946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005936517,"about_ca_system_score_gemma":0.00102866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002018163,"about_ca_topic_score_gemma":0.0001029528,"domain_scores_codex":[0.9982585,0.00005799343,0.0004230872,0.0004928653,0.0004848253,0.0002827692],"domain_scores_gemma":[0.9983561,0.000135097,0.0005168173,0.0005285351,0.0002634813,0.0001999662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1393547,0.02419208,0.8149403,0.0001427425,0.00359858,0.001383164,0.006424554,0.00001949446,0.002756903,0.00008511134,0.0001886959,0.006913632],"study_design_scores_gemma":[0.5337425,0.006558012,0.4561384,0.0001101673,0.0007548053,0.0000173382,0.00004980956,0.0001375912,0.002235797,0.00001344156,0.00003173546,0.0002103635],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970706,0.00005640139,0.000005856596,0.000266118,0.000162042,0.001614494,0.000423107,0.00002422393,0.0003771544],"genre_scores_gemma":[0.9979103,0.0003914182,0.0006074735,0.0001223811,0.0003733429,0.0001044756,0.0004140663,0.00004511586,0.00003144273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3943878,"threshold_uncertainty_score":0.9999939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01066105177175042,"score_gpt":0.2896659076061985,"score_spread":0.2790048558344481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}