{"id":"W3016364844","doi":"10.3390/cells9040992","title":"Hypoxia-Driven Immune Escape in the Tumor Microenvironment","year":2020,"lang":"en","type":"review","venue":"Cells","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":264,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Hypoxia (environmental); Tumor microenvironment; Immune system; Immunotherapy; Biology; Programmed cell death; Immune escape; Cancer research; Immunology; Apoptosis; Chemistry; Oxygen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002059989,0.0004488043,0.0006386489,0.001084093,0.0001872563,0.0007347945,0.0003586882,0.0006377411,0.002269905],"category_scores_gemma":[0.0002501338,0.0001318519,0.0002580386,0.001042848,0.0002534491,0.0007519832,0.0004451197,0.0009834705,0.001360662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004023954,"about_ca_system_score_gemma":0.0005760457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005258163,"about_ca_topic_score_gemma":0.0009134315,"domain_scores_codex":[0.9999324,0.00001054543,0.000007289804,0.0000131054,0.00002640939,0.00001018283],"domain_scores_gemma":[0.9999245,0.00003095639,0.00001226403,0.000002409242,0.00001968369,0.00001019383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007308154,0.00005693583,0.0002471195,0.01397522,0.00006341161,0.0003532242,0.00007478665,0.0005025984,0.007145206,0.006188138,0.02762337,0.9436969],"study_design_scores_gemma":[0.000009072321,0.00009473466,0.0009652026,0.002155669,0.00006241498,0.002018228,0.00005763669,0.0001133578,0.001534406,0.002664978,0.9903098,0.00001451323],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003046121,0.9973584,0.0002131621,0.0003094179,0.0001738853,0.000004209154,0.0000228159,0.000009948213,0.001603634],"genre_scores_gemma":[0.001288871,0.9974994,0.0001321071,0.0001457766,0.0001003405,0.00000576937,0.00003257269,0.000001440581,0.0007936736],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002269905,"threshold_uncertainty_score":0.007593572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01451174365181347,"score_gpt":0.2507048307245335,"score_spread":0.2361930870727201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}