{"id":"W3016364844","doi":"10.3390/cells9040992","title":"Hypoxia-Driven Immune Escape in the Tumor Microenvironment","year":2020,"lang":"en","type":"review","venue":"Cells","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":264,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Hypoxia (environmental); Tumor microenvironment; Immune system; Immunotherapy; Biology; Programmed cell death; Immune escape; Cancer research; Immunology; Apoptosis; Chemistry; Oxygen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001621041,0.0003743883,0.0008281246,0.00004061656,0.00004289868,0.00003158201,0.0006722593,0.0002077423,0.00005898709],"category_scores_gemma":[0.0000147831,0.000267942,0.0005112453,0.0001201177,0.00007894497,0.000001420705,0.0002152689,0.0003142205,0.0002347781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003002497,"about_ca_system_score_gemma":0.0001569716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001150314,"about_ca_topic_score_gemma":0.000007755953,"domain_scores_codex":[0.9983833,0.0001985765,0.0004336293,0.000522905,0.0001446861,0.000316846],"domain_scores_gemma":[0.9990305,0.00001953106,0.000203645,0.0006662753,0.000008076101,0.00007198166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001778535,0.0001533683,7.787887e-7,0.002826495,0.0001820378,0.00003953151,0.0001331421,0.000005231514,0.05354078,0.00001619898,0.03108782,0.9119968],"study_design_scores_gemma":[0.0002053263,0.00005149565,0.00000640389,0.0003808497,0.0002228739,0.00003940121,0.00002635866,6.176338e-7,0.001933675,0.000002212823,0.9968405,0.000290291],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001189825,0.9972577,0.00001260539,0.00005032331,0.0009672415,0.0007054711,0.00007936769,0.000005677811,0.0008026127],"genre_scores_gemma":[0.00004733335,0.9962768,0.0001163406,0.0004061203,0.001843056,0.0001343721,0.0002601694,0.00005673596,0.0008590738],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9657527,"threshold_uncertainty_score":0.9999773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01451174365181347,"score_gpt":0.2507048307245335,"score_spread":0.2361930870727201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}