{"id":"W3016525618","doi":"10.1016/j.ymthe.2020.04.013","title":"Check and Checkmate: Battling Cancer with Multiplex Immunotherapy","year":2020,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Oncolytic virus; Cancer; Cancer immunotherapy; Immunotherapy; Tumor microenvironment; Cancer immunology; Medicine; Immune system; Immune checkpoint; Cancer research; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001362454,0.0007053098,0.0006629021,0.00139819,0.000702501,0.003223365,0.0009984743,0.001488391,0.01322428],"category_scores_gemma":[0.001723348,0.0003454674,0.0007723377,0.0007145283,0.001299101,0.004366057,0.002007427,0.003532519,0.004346154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001019757,"about_ca_system_score_gemma":0.0008840793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005214342,"about_ca_topic_score_gemma":0.001617077,"domain_scores_codex":[0.9993148,0.0001371701,0.00002712627,0.00009249856,0.0003090106,0.0001193215],"domain_scores_gemma":[0.9993206,0.0002210232,0.00008054315,0.00007844578,0.00009797955,0.0002014194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006412811,0.0003631385,0.0008061037,0.001379229,0.0001918279,0.0004584321,0.0002090717,0.001491255,0.0280678,0.04628824,0.2077422,0.7123614],"study_design_scores_gemma":[0.0001667717,0.0006171223,0.000588568,0.00044456,0.000129461,0.001138368,0.0001521029,0.003697864,0.03015852,0.03185726,0.9309587,0.00009077768],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.04618613,0.4721999,0.1877774,0.1363376,0.03910346,0.0007058347,0.001571798,0.008874995,0.1072429],"genre_scores_gemma":[0.3642499,0.2945715,0.1313863,0.06558695,0.01566381,0.0007905696,0.001954162,0.001617936,0.124179],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.01322428,"threshold_uncertainty_score":0.04423958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03190717010889309,"score_gpt":0.3053762519500328,"score_spread":0.2734690818411397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}