{"id":"W3016536134","doi":"10.1371/journal.ppat.1008496","title":"Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration","year":2020,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Shelterin; Telomere; Biology; Telomere-binding protein; Gene knockdown; Viral protein; Viral replication; Genome; Immunoprecipitation; Chromatin; Virology; Molecular biology; Genetics; Gene; DNA-binding protein; Virus; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001035174,0.0003443428,0.0001897377,0.0002253766,0.0002926186,0.000398,0.0001426059,0.0004065973,0.0008979411],"category_scores_gemma":[0.00009957579,0.00012281,0.0002842454,0.0000830969,0.0001739953,0.0002472562,0.0003205873,0.0003701886,0.0003676826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000228201,"about_ca_system_score_gemma":0.0001670613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006436758,"about_ca_topic_score_gemma":0.0006292124,"domain_scores_codex":[0.9999148,0.00001164765,0.000006433902,0.00002398207,0.00002382128,0.00001932712],"domain_scores_gemma":[0.999948,0.000004857948,0.00001488085,0.000005204914,0.000008029784,0.00001903103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001155945,0.00003371737,0.001511868,0.00006363656,0.00001073471,0.0002368768,0.00003087251,0.00007418809,0.9946942,0.0002013653,0.0001137325,0.002913097],"study_design_scores_gemma":[0.0000603396,0.0004197923,0.118189,0.00006464523,0.00005090027,0.003778783,0.0002367657,0.004939808,0.857064,0.0002983244,0.01486679,0.0000308007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802226,0.01438211,0.003286501,0.0001654491,0.00004313787,0.00002353164,0.0002955747,0.00009290495,0.001488237],"genre_scores_gemma":[0.9942703,0.001865374,0.001434691,0.0000454721,0.0000148357,0.00001812086,0.0005330567,0.000008510768,0.001809638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008979411,"threshold_uncertainty_score":0.003003895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0615962196946348,"score_gpt":0.3142401084434381,"score_spread":0.2526438887488033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}