{"id":"W3016683260","doi":"10.3747/co.27.5549","title":"Biomarkers of Immune Checkpoint Inhibitor Efficacy in Cancer","year":2020,"lang":"en","type":"review","venue":"Current Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Manitoba Beekeepers' Association; CancerCare Manitoba; University of Calgary","funders":"","keywords":"Medicine; Cancer; Immune checkpoint; Immune system; Computational biology; Cancer research; Bioinformatics; Oncology; Internal medicine; Immunology; Immunotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001377865,0.0008800585,0.002172644,0.00207006,0.0001279057,0.001105793,0.000841207,0.001007137,0.001884527],"category_scores_gemma":[0.001783299,0.0003039568,0.0007708013,0.001741388,0.0003906932,0.0008854906,0.0006165407,0.001521944,0.0009504007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007166642,"about_ca_system_score_gemma":0.0008601512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007203192,"about_ca_topic_score_gemma":0.001255075,"domain_scores_codex":[0.9996288,0.0001052499,0.00006085066,0.00005700505,0.0001219814,0.00002603798],"domain_scores_gemma":[0.99924,0.0004297017,0.0001452743,0.00001458598,0.0001453816,0.00002505995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001294676,0.00005065747,0.000441176,0.01764644,0.0003038799,0.00006980319,0.00002313986,0.0003594382,0.0009040145,0.002170074,0.01138871,0.9665131],"study_design_scores_gemma":[0.0001161267,0.0004844638,0.005579969,0.02381382,0.001220408,0.001574793,0.00008083203,0.0006023726,0.001749409,0.005239669,0.9594723,0.00006584922],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008692607,0.9993964,0.00005865636,0.0001287535,0.0000687004,0.00000354161,0.00001314841,0.00000293128,0.0002408647],"genre_scores_gemma":[0.001616912,0.9976341,0.0001588008,0.0001990456,0.0001047133,0.0000121073,0.0000367121,9.852242e-7,0.0002365906],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002172644,"threshold_uncertainty_score":0.007286966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1784300429430428,"score_gpt":0.4708465286820926,"score_spread":0.2924164857390498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}