{"id":"W3016707213","doi":"10.1186/s12883-020-01728-x","title":"Predicting MCI progression with FDG-PET and cognitive scores: a longitudinal study","year":2020,"lang":"en","type":"article","venue":"BMC Neurology","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Key Research and Development Program of China; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Fundamental Research Funds for the Central Universities; National Institutes of Health; Servier; H. Lundbeck A/S; Foundation for the National Institutes of Health; Natural Science Foundation of Beijing Municipality; National Natural Science Foundation of China; Eisai; Genentech; IXICO; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Alzheimer's Association","keywords":"Medicine; Neurochemistry; Neurology; Neurosurgery; Cognition; Positron emission tomography; Internal medicine; Oncology; Medical physics; Nuclear medicine; Radiology; Psychiatry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002109594,0.0004994365,0.0004568684,0.0006296377,0.0006616088,0.0007661153,0.000342143,0.0007477593,0.000604334],"category_scores_gemma":[0.001924447,0.000342139,0.0006332666,0.0005604436,0.0002571435,0.0006600957,0.000345078,0.0009004673,0.0002702459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003031482,"about_ca_system_score_gemma":0.0003471485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003380446,"about_ca_topic_score_gemma":0.003551913,"domain_scores_codex":[0.999681,0.00008355513,0.00002391855,0.0001058283,0.00005500355,0.00005059767],"domain_scores_gemma":[0.9991158,0.0001027477,0.0002009174,0.0001297761,0.0002391961,0.0002116455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007387926,0.0003086106,0.9942576,0.000008638253,0.0001581668,0.00009953559,0.0001120211,0.00007506509,0.0003862857,0.00001446426,0.0001217386,0.00371906],"study_design_scores_gemma":[0.0000598777,0.001116723,0.9963391,0.00001306005,0.0002301708,0.0003544209,0.0001517692,0.001061368,0.0002514403,0.00006801209,0.000341754,0.00001240533],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991608,0.0002914838,0.0001930736,0.000032567,0.000009045953,0.00001653642,0.0001314678,0.0000057805,0.0001592644],"genre_scores_gemma":[0.9990695,0.0001237235,0.0002564302,0.00002347226,0.00001308221,0.00002037249,0.0003423537,0.000002523482,0.0001484635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003380446,"threshold_uncertainty_score":0.01115668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04988732546980624,"score_gpt":0.3532203158862919,"score_spread":0.3033329904164857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}