{"id":"W3016716571","doi":"10.1016/j.annonc.2020.04.005","title":"A multicentre, randomised trial comparing schedules of G-CSF (filgrastim) administration for primary prophylaxis of chemotherapy-induced febrile neutropenia in early stage breast cancer","year":2020,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Neutropenia and Cancer Infections","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"Northeast Cancer Centre; Western University; McMaster University; London Health Sciences Centre; Grand River Hospital; Thunder Bay Regional Research Institute; University of Ottawa; Ottawa Hospital","funders":"Canadian Institutes of Health Research; Cancer Care Ontario","keywords":"Filgrastim; Medicine; Febrile neutropenia; Neutropenia; Breast cancer; Randomized controlled trial; Internal medicine; Chemotherapy; Granulocyte colony-stimulating factor; Pegfilgrastim; Surgery; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001920819,0.001432659,0.00418028,0.0004983577,0.0004605767,0.001071497,0.001248609,0.002227293,0.007425322],"category_scores_gemma":[0.004115893,0.0007731178,0.002194267,0.0006269956,0.001263157,0.001198086,0.000697326,0.003730049,0.0008534644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001297674,"about_ca_system_score_gemma":0.001511846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00201886,"about_ca_topic_score_gemma":0.00315487,"domain_scores_codex":[0.9984876,0.0008653843,0.0001187631,0.0002547476,0.00007533113,0.000198148],"domain_scores_gemma":[0.9976928,0.0009146249,0.0004640261,0.0002138961,0.0001056153,0.0006090151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.993448,0.001563279,0.0001186673,0.0001941709,0.0003641202,0.000009697438,0.00001821074,0.000131867,0.000528716,0.00003338549,0.0001010894,0.003488867],"study_design_scores_gemma":[0.9597344,0.03881675,0.0006941446,0.00002216943,0.0002752491,0.0000118039,0.00001116634,0.0001305175,0.00007978587,0.00006210105,0.0001544184,0.000007483329],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987229,0.005761352,0.0006516046,0.0004961471,0.001058701,0.003080828,0.0004918131,0.0000681857,0.001162339],"genre_scores_gemma":[0.9900064,0.0019899,0.001497103,0.0006969746,0.0005041081,0.002921659,0.0005002366,0.00002176593,0.00186194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007425322,"threshold_uncertainty_score":0.02484012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1043781769812129,"score_gpt":0.3900628132249466,"score_spread":0.2856846362437336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}