{"id":"W3016737984","doi":"10.1016/j.jaip.2020.03.041","title":"Efficacy and Safety of Ragweed SLIT-Tablet in Children with Allergic Rhinoconjunctivitis in a Randomized, Placebo-Controlled Trial","year":2020,"lang":"en","type":"article","venue":"The Journal of Allergy and Clinical Immunology In Practice","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Merck Sharp and Dohme; Allergopharma; Pearl Therapeutics; Genentech; Allergy Therapeutics; Mylan; BioCryst; Sun Pharma; Regeneron Pharmaceuticals; Teva Pharmaceutical Industries; Novartis; Sanofi; GlaxoSmithKline; Merck; Takeda Pharmaceuticals U.S.A.; Boehringer Ingelheim; Amgen; Pfizer; Shire; AstraZeneca","keywords":"Medicine; Ragweed; Placebo; Randomized controlled trial; Sublingual immunotherapy; Slit; Allergic conjunctivitis; Allergy; Internal medicine; Alternative medicine; Immunology; Allergen; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002043466,0.001614436,0.005612243,0.0004789899,0.0006095431,0.001235006,0.001148779,0.003014775,0.004488709],"category_scores_gemma":[0.002646299,0.0009217625,0.00310212,0.0004743218,0.001744726,0.001248791,0.0004758661,0.003249745,0.0006108216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007469801,"about_ca_system_score_gemma":0.001090695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001209152,"about_ca_topic_score_gemma":0.00195079,"domain_scores_codex":[0.9984179,0.000729682,0.0001528617,0.0003640352,0.0001425548,0.0001930592],"domain_scores_gemma":[0.99829,0.0006508636,0.00042401,0.0001327523,0.0001137304,0.0003886416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9864997,0.003268333,0.0009041636,0.0006951218,0.001037819,0.00006518536,0.00004934245,0.0001038192,0.001614728,0.00006017614,0.0001864797,0.005515142],"study_design_scores_gemma":[0.9325494,0.06204151,0.003635155,0.00004732198,0.0009017663,0.00003351058,0.00003113082,0.0001748065,0.0002695306,0.00004696079,0.0002551991,0.00001368375],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891582,0.006909296,0.0003377496,0.0003460336,0.0004134747,0.001563792,0.0004649182,0.00005552527,0.0007511175],"genre_scores_gemma":[0.9919506,0.002981981,0.0009355978,0.0004712589,0.0004659985,0.001728014,0.0004480237,0.00001535764,0.001003139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005612243,"threshold_uncertainty_score":0.0150162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01615456670730828,"score_gpt":0.2993801523330569,"score_spread":0.2832255856257486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}