{"id":"W3016737984","doi":"10.1016/j.jaip.2020.03.041","title":"Efficacy and Safety of Ragweed SLIT-Tablet in Children with Allergic Rhinoconjunctivitis in a Randomized, Placebo-Controlled Trial","year":2020,"lang":"en","type":"article","venue":"The Journal of Allergy and Clinical Immunology In Practice","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Merck Sharp and Dohme; Allergopharma; Pearl Therapeutics; Genentech; Allergy Therapeutics; Mylan; BioCryst; Sun Pharma; Regeneron Pharmaceuticals; Teva Pharmaceutical Industries; Novartis; Sanofi; GlaxoSmithKline; Merck; Takeda Pharmaceuticals U.S.A.; Boehringer Ingelheim; Amgen; Pfizer; Shire; AstraZeneca","keywords":"Medicine; Ragweed; Placebo; Randomized controlled trial; Sublingual immunotherapy; Slit; Allergic conjunctivitis; Allergy; Internal medicine; Alternative medicine; Immunology; Allergen; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.005440724,0.0001740809,0.00180392,0.0001390206,0.00003793716,0.00001069491,0.000113572,0.0002384707,0.00003674252],"category_scores_gemma":[0.008369314,0.0001023116,0.0001203918,0.0002243842,0.0004909296,0.0002539041,0.00005934234,0.001245457,9.784919e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002289647,"about_ca_system_score_gemma":0.0002049408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001711292,"about_ca_topic_score_gemma":0.0001230297,"domain_scores_codex":[0.9942967,0.003197131,0.001919987,0.0001857022,0.0002073193,0.0001932156],"domain_scores_gemma":[0.9892488,0.009141702,0.001240904,0.0001424351,0.000144108,0.00008212675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9895127,0.0007580593,0.001540204,0.000003566664,0.00427341,0.0001413947,0.001368975,0.0002805359,0.00004664677,0.0003211491,0.00001541907,0.001737895],"study_design_scores_gemma":[0.9344649,0.004101087,0.05763929,0.0001805554,0.0007380959,0.001003465,0.000872883,0.0007008541,0.000005742291,0.00009467491,0.00009971359,0.00009879891],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980867,0.003486068,0.00009621086,0.01313951,0.0001066557,0.001525637,6.466449e-7,0.000004061465,0.0007742405],"genre_scores_gemma":[0.9621687,0.03632995,0.000277522,0.00106078,0.0001143787,0.000008164126,0.000002681002,0.00001285003,0.00002496361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05609908,"threshold_uncertainty_score":0.9999836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01615456670730828,"score_gpt":0.2993801523330569,"score_spread":0.2832255856257486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}