{"id":"W3016787650","doi":"10.1096/fasebj.2020.34.s1.03450","title":"Mutation of <i>Eftud2</i> in Mouse Neural Crest Cells Models MFDM and Reveals Contribution of P53 in Abnormal Craniofacial Development","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Craniofacial Disorders and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Neural crest; Biology; Exencephaly; Neural tube; Embryo; Craniofacial; Genetics; Exon; Haploinsufficiency; Cranial neural crest; Phenotype; Gene; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001898401,0.0004968437,0.0002205103,0.000468231,0.0002647513,0.000276076,0.0003955622,0.0006161967,0.00194692],"category_scores_gemma":[0.0001695543,0.0002908364,0.0004723571,0.0002129978,0.0004032791,0.0001796691,0.0004434929,0.0008037902,0.0007056591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003042682,"about_ca_system_score_gemma":0.0001453006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001071672,"about_ca_topic_score_gemma":0.002222315,"domain_scores_codex":[0.9997154,0.00002928813,0.00004387412,0.00007714657,0.00006959237,0.00006466365],"domain_scores_gemma":[0.9997994,0.0000378153,0.00007035432,0.00002614373,0.00001175575,0.00005450208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003181165,0.00001182581,0.0002413351,0.00001388476,0.000003272562,0.0001988643,0.00001128925,0.00003688545,0.998774,0.00006769717,0.00002117135,0.0005879823],"study_design_scores_gemma":[0.00001638271,0.00009859652,0.008050053,0.000009599996,0.00001631203,0.001382476,0.00003996525,0.000857274,0.9870567,0.00003187922,0.002434395,0.000006302289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912871,0.0005273918,0.004420251,0.0001146974,0.00003243076,0.000068497,0.0008612232,0.0001417171,0.00254677],"genre_scores_gemma":[0.9875193,0.0004632059,0.005984816,0.0001031544,0.00001038238,0.00009748271,0.001204972,0.00009558902,0.00452108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00194692,"threshold_uncertainty_score":0.006513119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01249053434755607,"score_gpt":0.2266635224613349,"score_spread":0.2141729881137788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}