{"id":"W3016845921","doi":"10.1182/blood.v110.11.3553.3553","title":"A Phase II Trial of the Small Molecule Pan-Bcl-2 Family Inhibitor Obatoclax Mesylate (GX15-070) Administered by a 24-h Continuous Infusion Every 2 Weeks to Patients with Chronic Idiopathic Myelofibrosis (CIMF).","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Chills; Nausea; Anemia; Internal medicine; Peripheral edema; Erythropoietin; Adverse effect; Gastroenterology; Rash","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009711301,0.001380488,0.001150213,0.0003824466,0.0002764258,0.000634627,0.0006868139,0.001065807,0.003949353],"category_scores_gemma":[0.0005210506,0.0004633724,0.0008068256,0.000246522,0.0008210419,0.0007386943,0.000314079,0.002313367,0.0007920216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005782268,"about_ca_system_score_gemma":0.0007477205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006688897,"about_ca_topic_score_gemma":0.00187119,"domain_scores_codex":[0.9997818,0.00009742421,0.000007372092,0.00003478899,0.00001799213,0.00006068101],"domain_scores_gemma":[0.9996265,0.00006536431,0.0000540337,0.00002900502,0.00001731652,0.0002078748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8054514,0.05232582,0.004720076,0.0005983764,0.0005867877,0.0003593744,0.0002831053,0.00172586,0.03895432,0.0006291694,0.003918804,0.09044688],"study_design_scores_gemma":[0.6431962,0.3448409,0.006415879,0.00002542261,0.0001297165,0.0002289256,0.00004767535,0.0009593968,0.002152207,0.0001912987,0.001793615,0.00001868208],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941697,0.00125823,0.0003301186,0.0003945334,0.0001543717,0.001560104,0.0005165301,0.00006126898,0.001555085],"genre_scores_gemma":[0.9904051,0.00123252,0.001010908,0.0007203683,0.0001356531,0.001680935,0.001637001,0.00001439761,0.003163172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003949353,"threshold_uncertainty_score":0.01321185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01368548042332383,"score_gpt":0.2639499997712481,"score_spread":0.2502645193479243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}