{"id":"W3016845921","doi":"10.1182/blood.v110.11.3553.3553","title":"A Phase II Trial of the Small Molecule Pan-Bcl-2 Family Inhibitor Obatoclax Mesylate (GX15-070) Administered by a 24-h Continuous Infusion Every 2 Weeks to Patients with Chronic Idiopathic Myelofibrosis (CIMF).","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Chills; Nausea; Anemia; Internal medicine; Peripheral edema; Erythropoietin; Adverse effect; Gastroenterology; Rash","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008711031,0.0004641619,0.0008911367,0.0002255901,0.000223784,0.00004117738,0.0004840455,0.0003339733,0.00002666766],"category_scores_gemma":[0.0005041937,0.0003159093,0.0002706364,0.0008479225,0.0002510395,0.00009053187,0.0005228849,0.0004965285,0.00003368792],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003111205,"about_ca_system_score_gemma":0.006728336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006876515,"about_ca_topic_score_gemma":0.0002455044,"domain_scores_codex":[0.9955858,0.0001817701,0.00104293,0.0007275481,0.001479069,0.0009828745],"domain_scores_gemma":[0.9973135,0.0001611421,0.0004080081,0.001196515,0.0004317639,0.0004890678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2168956,0.03846373,0.003472037,0.001333086,0.001125075,0.0004808891,0.003138501,0.000003704208,0.6955983,0.00002631388,0.00398146,0.03548132],"study_design_scores_gemma":[0.6893815,0.04250898,0.00234313,0.001668431,0.0006220263,0.00006719895,0.0001345827,0.00009661142,0.259896,0.000006362733,0.002767642,0.0005074623],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935198,0.0008778694,0.00005884984,0.0001692106,0.0003675135,0.004267076,0.0001042853,0.00008516071,0.0005501846],"genre_scores_gemma":[0.9978411,0.00004572596,0.0001774807,0.0003204341,0.0003794644,0.0001537726,0.00005666249,0.0001019469,0.0009233957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.472486,"threshold_uncertainty_score":0.9999293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01368548042332383,"score_gpt":0.2639499997712481,"score_spread":0.2502645193479243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}