{"id":"W3016911114","doi":"10.1002/cbic.201900689","title":"Dual‐PKS Cluster for Biosynthesis of a Light‐Induced Secondary Metabolite Found from Genome Sequencing of <i>Hyphodiscus hymeniophilus</i> Fungus","year":2020,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Fungus; Secondary metabolite; Genome; Biology; Gene cluster; Metabolite; Gene; Whole genome sequencing; Homology (biology); Genetics; Biosynthesis; Computational biology; Biochemistry; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002471502,0.0003409311,0.00102797,0.00009472167,0.00005827222,0.00001754121,0.000217479,0.0002538556,0.0002965249],"category_scores_gemma":[0.0005038835,0.0002642519,0.0004276963,0.0003289818,0.00009760269,0.00009830271,0.0001433647,0.000233366,0.00001326553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000072209,"about_ca_system_score_gemma":0.0002242534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008289543,"about_ca_topic_score_gemma":0.000003668663,"domain_scores_codex":[0.9979468,0.00003629459,0.0007432108,0.0006479537,0.0002570289,0.0003687112],"domain_scores_gemma":[0.9984027,0.0001725376,0.000385339,0.0005142596,0.000285699,0.0002394473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007326762,0.00008368427,0.00001649831,0.0008190381,0.0004021681,0.000007788101,0.0009887257,2.610215e-7,0.9934107,0.00002386669,0.001001179,0.002513411],"study_design_scores_gemma":[0.001641221,0.0002313909,0.0001879182,0.0001259691,0.0006157457,0.00001406234,0.0003364206,0.00002181043,0.9864942,0.00008236478,0.009961877,0.0002870271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855766,0.003544566,0.0000300592,0.008053555,0.0001649614,0.0008643645,0.0007299036,0.00005323337,0.0009827821],"genre_scores_gemma":[0.9931337,0.0000675332,0.003773391,0.001724775,0.0008466116,0.000006521243,0.0001635431,0.0000599751,0.0002239236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008960698,"threshold_uncertainty_score":0.999981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03199131745914133,"score_gpt":0.2407538426070114,"score_spread":0.2087625251478701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}