{"id":"W3016911114","doi":"10.1002/cbic.201900689","title":"Dual‐PKS Cluster for Biosynthesis of a Light‐Induced Secondary Metabolite Found from Genome Sequencing of <i>Hyphodiscus hymeniophilus</i> Fungus","year":2020,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Fungus; Secondary metabolite; Genome; Biology; Gene cluster; Metabolite; Gene; Whole genome sequencing; Homology (biology); Genetics; Biosynthesis; Computational biology; Biochemistry; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005467143,0.0003332369,0.0002706345,0.0003753613,0.0003072989,0.0004045817,0.0001274803,0.0001985394,0.001322828],"category_scores_gemma":[0.00009649158,0.000121588,0.0003053772,0.0003268151,0.0001231496,0.000182565,0.0002478338,0.0003612593,0.0005075014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003566686,"about_ca_system_score_gemma":0.0004489768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00165014,"about_ca_topic_score_gemma":0.001933244,"domain_scores_codex":[0.9999193,0.000004978684,0.000005289561,0.00003094018,0.00002564373,0.00001387323],"domain_scores_gemma":[0.999889,0.00001249695,0.0000354666,0.000009255456,0.00001421227,0.00003956249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001649603,0.00002309569,0.001783785,0.00006992748,0.000006846274,0.000118621,0.00004475812,0.00006133044,0.9954259,0.00007779164,0.00007491829,0.002148019],"study_design_scores_gemma":[0.0000510401,0.0002888246,0.2584402,0.00004518872,0.0001149909,0.001484224,0.0004078598,0.003118059,0.723879,0.0003091374,0.01183069,0.00003073414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871835,0.0007530143,0.003891949,0.00009322072,0.00002357951,0.00006142521,0.006074182,0.000191342,0.00172789],"genre_scores_gemma":[0.9728211,0.0004703351,0.009507756,0.00006351649,0.00001249183,0.00005054336,0.01376436,0.00005397041,0.003255819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00165014,"threshold_uncertainty_score":0.004425347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03199131745914133,"score_gpt":0.2407538426070114,"score_spread":0.2087625251478701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}