{"id":"W3016940607","doi":"10.1007/s00408-020-00353-2","title":"Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis","year":2020,"lang":"en","type":"article","venue":"Lung","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Cystic Fibrosis Canada","keywords":"Cystic fibrosis; Ceramide; Medicine; Internal medicine; Lung; Endocrinology; Airway resistance; Fibrosis; Hyperplasia; Knockout mouse; Pathology; Andrology; Chemistry; Apoptosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001822834,0.0001825464,0.0004092338,0.00009840422,0.0000462223,0.00002331659,0.0001196049,0.00009312155,0.0000241445],"category_scores_gemma":[0.000748714,0.0001642042,0.0000331502,0.0003358845,0.00008665365,0.0001028052,0.0001751934,0.0004436995,0.000001936823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002729566,"about_ca_system_score_gemma":0.00006710964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001898113,"about_ca_topic_score_gemma":0.0001853356,"domain_scores_codex":[0.9981715,0.0001593863,0.0003383422,0.0005003566,0.0003548347,0.0004755774],"domain_scores_gemma":[0.9992868,0.0001480698,0.00007674246,0.0002144028,0.00003010262,0.0002439013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007951101,0.00008516922,0.258972,0.0008364692,0.00001336153,0.0004096947,0.0007621397,0.00005015359,0.7340578,0.000007348096,0.0005539096,0.003456884],"study_design_scores_gemma":[0.006929789,0.001359822,0.8548446,0.003508873,0.00005639716,0.00003674824,0.000457243,0.02265324,0.1081098,0.0002109712,0.001272192,0.0005602903],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903143,0.005808661,0.0002075778,0.002543,0.00006818768,0.0008852922,0.00003909278,0.00006080733,0.00007308728],"genre_scores_gemma":[0.9960759,0.000386615,0.002869114,0.0002467248,0.00007451526,0.00018178,0.00006647464,0.00002867655,0.00007019155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.625948,"threshold_uncertainty_score":0.6696052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01304412598203693,"score_gpt":0.3096204426181488,"score_spread":0.2965763166361119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}