{"id":"W3016983802","doi":"10.1016/j.actbio.2020.04.016","title":"Engineering blood outgrowth endothelial cells to optimize endothelial nitric oxide synthase and extracellular matrix production for coating of blood contacting surfaces","year":2020,"lang":"en","type":"article","venue":"Acta Biomaterialia","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Enos; Umbilical vein; Fibronectin; Extracellular matrix; Cell biology; Nitric oxide; Biology; Chemistry; Nitric oxide synthase; Biochemistry; Endocrinology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003279292,0.0003272528,0.0002608526,0.0001905508,0.0001535948,0.0004792301,0.0002501193,0.000414322,0.0004262426],"category_scores_gemma":[0.0002585361,0.0001872265,0.0002515966,0.0002066406,0.0001429042,0.0001577852,0.0002278553,0.0003774007,0.0002273258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003038673,"about_ca_system_score_gemma":0.0002530743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006969706,"about_ca_topic_score_gemma":0.001822115,"domain_scores_codex":[0.9997631,0.00004004419,0.00002287951,0.00003338397,0.00008854789,0.00005207488],"domain_scores_gemma":[0.9998679,0.00003454877,0.0000287446,0.00001492329,0.00003351175,0.00002033754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009610624,0.00001254835,0.00004994866,0.00001058936,0.000001840626,0.00001631975,0.000009450424,0.0001435258,0.9990407,0.00008040587,0.00001078756,0.0006142994],"study_design_scores_gemma":[0.000002560671,0.00003181361,0.0002678442,0.000001717444,0.000004751228,0.00002315132,0.00000680593,0.0009054368,0.9980273,0.00001754498,0.0007091757,0.000001909933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9619732,0.00121703,0.03335908,0.00006821813,0.00007004666,0.00007447146,0.0001447736,0.0001024941,0.002990643],"genre_scores_gemma":[0.9705763,0.0006220423,0.02532928,0.00004519676,0.000009307428,0.00004908743,0.0001696518,0.00003949774,0.003159601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006969706,"threshold_uncertainty_score":0.002204716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01327727706998952,"score_gpt":0.2367497042163093,"score_spread":0.2234724271463198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}