{"id":"W3017002183","doi":"10.1096/fasebj.2020.34.s1.04156","title":"Structural and Functional Insights into TAZ2‐mediated CBP/p300 Recruitment by the Melanogenic Transcription Factor MITF","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Microphthalmia-associated transcription factor; Transactivation; Transcription factor; IRF4; CREB; Biology; Transcription (linguistics); Basic helix-loop-helix; Leucine zipper; Cell biology; Chromatin immunoprecipitation; Molecular biology; Chemistry; Gene; Genetics; Promoter; DNA-binding protein; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000913262,0.0003709026,0.0001949735,0.0001101231,0.0001975806,0.0001834112,0.0004745038,0.0003608929,0.001633363],"category_scores_gemma":[0.0001033544,0.0001251851,0.0002601334,0.000100296,0.0001892706,0.0001987744,0.000163775,0.0005378874,0.0005411268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000524963,"about_ca_system_score_gemma":0.0002020986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00218041,"about_ca_topic_score_gemma":0.001603858,"domain_scores_codex":[0.9999497,0.000005525847,0.000002255414,0.00001114377,0.00001678108,0.00001462],"domain_scores_gemma":[0.999963,0.000007096058,0.000007414241,0.000002803652,0.000004098956,0.00001563775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002731678,0.00003701444,0.0002697125,0.00006894471,0.000008893518,0.0002336435,0.00002279078,0.0006149125,0.9965795,0.0003037809,0.00009016816,0.001497551],"study_design_scores_gemma":[0.0001800305,0.0002881478,0.01345472,0.0000179845,0.00003019237,0.0009379378,0.0001475734,0.02883457,0.9493376,0.0005169254,0.006211685,0.00004256297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903881,0.00203801,0.004916305,0.0002991994,0.00002997164,0.00002884786,0.0004458644,0.00009030959,0.001763381],"genre_scores_gemma":[0.9951583,0.0007859895,0.002479182,0.00007738024,0.000008338699,0.0000161125,0.0005292189,0.00001083911,0.0009347094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00218041,"threshold_uncertainty_score":0.005464196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03998939869155833,"score_gpt":0.2518294135456443,"score_spread":0.211840014854086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}