{"id":"W3017048434","doi":"10.1097/tp.0000000000003078","title":"Targeting Calcium Release–activated Calcium Channel Is Not Sufficient to Prevent Rejection in Nonhuman Primate Kidney Transplantation","year":2020,"lang":"en","type":"article","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Petrel Robertson Consulting (Canada)","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Tacrolimus; Calcineurin; Medicine; Transplantation; Nephrotoxicity; Pharmacology; Ciclosporin; Kidney transplantation; Kidney; Transplant rejection; Immunosuppressive drug; Urology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003750962,0.0003315542,0.0004888498,0.0002791212,0.0003416518,0.0006107664,0.0003052971,0.0004047634,0.001620257],"category_scores_gemma":[0.0002778574,0.0001565841,0.0002938737,0.0001676449,0.0003955175,0.0003471252,0.000146302,0.000910603,0.0004141361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003597936,"about_ca_system_score_gemma":0.0004548901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005739284,"about_ca_topic_score_gemma":0.001300943,"domain_scores_codex":[0.9997543,0.00004816253,0.000021215,0.00004820002,0.00008275149,0.00004546198],"domain_scores_gemma":[0.9998131,0.0000304703,0.00006178996,0.00004057501,0.00002174987,0.00003240368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006922452,0.0003392226,0.000546203,0.0001111679,0.00002693981,0.0001531955,0.00005353249,0.0001346085,0.9927618,0.0001573308,0.0001516086,0.004872102],"study_design_scores_gemma":[0.0002669339,0.008872532,0.008734819,0.00004468824,0.0001506615,0.002988399,0.00009809531,0.001847712,0.9642239,0.0001855751,0.0125721,0.00001455803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917144,0.003726709,0.001799597,0.0001724776,0.00006327974,0.0001215796,0.0001383774,0.00008850798,0.002175061],"genre_scores_gemma":[0.9930413,0.002034958,0.002094368,0.0001414185,0.00003839213,0.0001768348,0.0003715589,0.00003068866,0.00207044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001620257,"threshold_uncertainty_score":0.005420327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03884648369272251,"score_gpt":0.3143609265071867,"score_spread":0.2755144428144641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}