{"id":"W3017083762","doi":"10.1096/fasebj.2020.34.s1.02630","title":"Peripherally Restricted Dual Cannabinoid Receptor Agonist Modifies Mitochondrial Signaling and Inhibits Atrial Electrical Remodeling in a Tachypaced <i>Ex Vivo</i> Rat Model","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Atrial fibrillation; Internal medicine; Medicine; Refractory period; Cardiology; Effective refractory period; Atrium (architecture); Electrophysiology; Nerve conduction velocity; Dronedarone; Endocrinology; Chemistry; Amiodarone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003370751,0.0005813839,0.0005613217,0.0003748828,0.0002507633,0.0002895371,0.0003927993,0.0004327353,0.001697124],"category_scores_gemma":[0.0001421163,0.0002296056,0.0006289494,0.0001804981,0.000422341,0.0004205812,0.0002209314,0.001425577,0.0004678805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002368314,"about_ca_system_score_gemma":0.0003267845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008631512,"about_ca_topic_score_gemma":0.001727585,"domain_scores_codex":[0.999788,0.00002371995,0.00002743133,0.0000573425,0.00003500697,0.00006847472],"domain_scores_gemma":[0.9998166,0.00001583965,0.00005052299,0.00002523408,0.00002013115,0.00007167649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001659314,0.0002909095,0.0002670022,0.00009221033,0.00001643859,0.000118436,0.00004106269,0.00008542599,0.995033,0.0001272349,0.0001678581,0.002101026],"study_design_scores_gemma":[0.0002690133,0.006760088,0.00802788,0.00003393171,0.0001263508,0.0003886895,0.0001590607,0.001776017,0.9796954,0.0001928394,0.002544428,0.00002625425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934443,0.001712538,0.002237202,0.0002437626,0.0001187076,0.00004672852,0.0005979012,0.0001470331,0.001451854],"genre_scores_gemma":[0.9907166,0.001891664,0.002346641,0.0001525459,0.00003680774,0.0001467724,0.0006181508,0.00003254715,0.004058092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001697124,"threshold_uncertainty_score":0.005677462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01742667657842972,"score_gpt":0.2433872961565214,"score_spread":0.2259606195780917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}