{"id":"W3017153652","doi":"10.20944/preprints202004.0315.v1","title":"In Search of Preventative Strategies: Novel Anti-Inflammatory High-CBD &lt;em&gt;Cannabis Sativa&lt;/em&gt; Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues","year":2020,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Lethbridge","funders":"","keywords":"Biology; Cannabidiol; Cannabis sativa; Inflammation; Pharmacology; Immunology; Medicine; Cannabis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328623,0.0003632802,0.0004479589,0.0005419838,0.0003009229,0.0004317184,0.0002728634,0.0003526798,0.004024882],"category_scores_gemma":[0.0001238091,0.0001316322,0.0004564958,0.000252578,0.0002634256,0.0003333455,0.00023026,0.000993256,0.0006407392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004392605,"about_ca_system_score_gemma":0.0003997459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001874175,"about_ca_topic_score_gemma":0.005662979,"domain_scores_codex":[0.9999318,0.000008043343,0.000004754982,0.00001395006,0.00002277195,0.00001864561],"domain_scores_gemma":[0.9999504,0.000006923095,0.00001033362,0.000005014583,0.00001233001,0.00001496525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001073839,0.0003205136,0.0008587376,0.0007462496,0.00005801102,0.0002462253,0.00004149848,0.0001982208,0.9669156,0.0005034457,0.001133694,0.02790401],"study_design_scores_gemma":[0.0003844283,0.004056848,0.02198721,0.0002596202,0.0003905027,0.001282924,0.0003094533,0.001728568,0.8861703,0.0009526876,0.08240523,0.00007226746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9319397,0.03905123,0.008188803,0.002272997,0.000408978,0.0003375589,0.003721824,0.0004534572,0.0136256],"genre_scores_gemma":[0.9530785,0.01901022,0.0101119,0.00142968,0.00008512824,0.0001805661,0.003074287,0.00007729976,0.01295255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004024882,"threshold_uncertainty_score":0.01346463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0876913096636423,"score_gpt":0.3871408274469825,"score_spread":0.2994495177833402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}