{"id":"W3017237990","doi":"10.1186/s13229-020-00334-5","title":"Emerging proteomic approaches to identify the underlying pathophysiology of neurodevelopmental and neurodegenerative disorders","year":2020,"lang":"en","type":"review","venue":"Molecular Autism","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Neurology; Neuroscience; Medicine; Pathophysiology; Neuropsychology; Bioinformatics; Psychiatry; Psychology; Pathology; Cognition; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001952774,0.001468024,0.001565696,0.003158448,0.0005721097,0.002166497,0.001189773,0.001572324,0.002614461],"category_scores_gemma":[0.001142558,0.000450324,0.001179687,0.002266293,0.001197918,0.002732923,0.001690365,0.003062808,0.00167599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001187658,"about_ca_system_score_gemma":0.001665732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001197084,"about_ca_topic_score_gemma":0.001455566,"domain_scores_codex":[0.9991364,0.0001710391,0.0000756419,0.0002190321,0.000325552,0.00007240829],"domain_scores_gemma":[0.9993761,0.0001635684,0.0001054415,0.00004063579,0.0002454549,0.00006882123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000385624,0.000213832,0.006524678,0.01942191,0.0008388372,0.002008901,0.0009544486,0.001194747,0.2623357,0.05235803,0.03439186,0.6193714],"study_design_scores_gemma":[0.00006459207,0.0005242714,0.02139958,0.004956179,0.0008454568,0.007591501,0.001440536,0.00463263,0.07818461,0.0662693,0.8138826,0.0002088335],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01287586,0.854704,0.09448563,0.009875519,0.001977528,0.0002899763,0.002013516,0.0008918848,0.02288613],"genre_scores_gemma":[0.05579326,0.8307052,0.09578031,0.005228689,0.001560923,0.0004389336,0.002084946,0.0001192541,0.008288625],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003158448,"threshold_uncertainty_score":0.01032734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06055744923325113,"score_gpt":0.30685219174637,"score_spread":0.2462947425131189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}