{"id":"W3017283443","doi":"10.1016/j.neubiorev.2020.04.012","title":"Maternal Immune Activation by Poly I:C as a preclinical Model for Neurodevelopmental Disorders: A focus on Autism and Schizophrenia","year":2020,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":196,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Autism; Schizophrenia (object-oriented programming); Offspring; Autism spectrum disorder; Neurodevelopmental disorder; Psychology; Immune system; Psychiatry; Neuroscience; Pregnancy; Medicine; Immunology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003870921,0.001092531,0.002114642,0.0002467851,0.0004922893,0.0004459413,0.001343752,0.0003623196,0.00002577127],"category_scores_gemma":[0.001404447,0.0008625017,0.0007825498,0.0008390079,0.0005483722,0.0005438211,0.0004332526,0.0009221726,0.0001114165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001100756,"about_ca_system_score_gemma":0.0004248329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000193363,"about_ca_topic_score_gemma":0.000003039681,"domain_scores_codex":[0.9940694,0.0003739835,0.001578411,0.002413874,0.0007094337,0.0008548842],"domain_scores_gemma":[0.9977881,0.00005119881,0.001043999,0.0006482859,0.00001523219,0.0004531457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006814212,0.0002325272,0.000002512649,0.0008473382,1.805514e-7,0.000005922823,0.00003275317,1.573825e-7,0.005894483,0.0003178033,0.0005498735,0.9920483],"study_design_scores_gemma":[0.000647646,0.0007098446,0.00006139076,0.002330046,0.0001086899,0.00005213108,0.000002289876,0.0005058103,0.0002209991,0.0002822453,0.9942454,0.000833512],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001144541,0.9909739,0.0006639629,0.0001877226,0.0006772972,0.005680698,0.000389039,0.000208457,0.00007431738],"genre_scores_gemma":[0.00381393,0.9924347,0.0004700579,0.001715457,0.00005045188,0.001056407,0.00002954839,0.0001363898,0.000293072],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9936955,"threshold_uncertainty_score":0.9993826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1326581331545675,"score_gpt":0.3915714200311447,"score_spread":0.2589132868765772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}