{"id":"W3017489078","doi":"10.1038/s41467-020-15891-9","title":"Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; McMaster University; European Commission; University of Toronto; University of Bern; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Novartis Foundation; National Science Foundation","keywords":"Virulence; Pathogenicity island; Biology; Microbiology; Pathogen; Immunity; Salmonella; Inflammasome; Immunogenicity; Virulence factor; Innate immune system; Acquired immune system; NOD2; Virology; Immunology; Inflammation; Antibody; Immune system; Bacteria; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000143456,0.0004356794,0.0002916847,0.0002235828,0.00009636625,0.0002587649,0.0002110007,0.0002793158,0.0008966044],"category_scores_gemma":[0.0001365022,0.0001393809,0.0002792461,0.00008096525,0.0003524193,0.0002452642,0.0004214614,0.0007161191,0.0001773898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001753238,"about_ca_system_score_gemma":0.0002168345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001464296,"about_ca_topic_score_gemma":0.0002567064,"domain_scores_codex":[0.9998562,0.00002905892,0.00001323459,0.00002373852,0.00003727576,0.00004036618],"domain_scores_gemma":[0.9997438,0.00003933821,0.00008204702,0.00004872919,0.00001359261,0.0000725628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001352487,0.00001839788,0.0001010133,0.00002102579,0.000001990017,0.00002982213,0.000003614352,0.00002886978,0.9991913,0.00006200564,0.00000726445,0.0003995008],"study_design_scores_gemma":[0.00002699786,0.0008325536,0.005247505,0.0000107841,0.00001045151,0.000387496,0.00002392722,0.0006638202,0.9919337,0.0001406502,0.0007170134,0.00000514772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969726,0.0003785268,0.001761472,0.00007201662,0.00001828117,0.00001342696,0.0001030998,0.00006425346,0.0006161744],"genre_scores_gemma":[0.9964703,0.0002825006,0.00206339,0.00003748899,0.000007625086,0.0000207912,0.0001434851,0.00002244196,0.0009519785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008966044,"threshold_uncertainty_score":0.002999425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02681440068177311,"score_gpt":0.2968189462224427,"score_spread":0.2700045455406696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}