{"id":"W3017791378","doi":"10.1016/j.exer.2020.108042","title":"AP-2β is required for formation of the murine trabecular meshwork and Schlemm's canal","year":2020,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; McMaster University Medical Centre; Health Sciences Centre","funders":"National Institutes of Health; National Eye Institute; Ontario Research Foundation","keywords":"Trabecular meshwork; Myocilin; Schlemm's canal; Cell biology; Embryogenesis; Biology; Neural crest; Embryonic stem cell; Cornea; Anatomy; Knockout mouse; Chemistry; Embryo; Glaucoma; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002225935,0.00007609014,0.0001520665,0.00004628728,0.0001444294,0.00001341769,0.000103879,0.00004833291,0.0001039611],"category_scores_gemma":[0.00008970129,0.00005070869,0.00008404248,0.0002310656,0.0002006151,0.00006338571,0.00009549882,0.0001533942,0.000005902607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004581141,"about_ca_system_score_gemma":0.00007013139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001579253,"about_ca_topic_score_gemma":0.000006322688,"domain_scores_codex":[0.9989002,0.00006255173,0.0001700632,0.0001584656,0.0004739662,0.0002347024],"domain_scores_gemma":[0.9995613,0.00003547364,0.00003096567,0.0001423789,0.00008904929,0.0001408059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001280467,0.0002185049,0.005960349,0.0004564441,0.00007065294,0.000009342783,0.009756286,4.388061e-7,0.9649186,0.001195482,0.01471991,0.001413518],"study_design_scores_gemma":[0.002433829,0.001134273,0.006581597,0.0001211651,0.00001905093,0.00001013507,0.009244743,0.002074621,0.9653115,0.0001048484,0.01287791,0.00008637181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804278,0.002439825,0.0000551068,0.01457334,0.00002996027,0.0008756996,0.00001065186,0.00001017528,0.00157744],"genre_scores_gemma":[0.9988309,0.00004626475,0.0002914568,0.0003702337,0.00006205345,0.00005482421,0.00001171912,0.00001323668,0.000319357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01840305,"threshold_uncertainty_score":0.206784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07656824084804002,"score_gpt":0.3983028531988461,"score_spread":0.321734612350806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}