{"id":"W3017921306","doi":"10.18433/jpps30847","title":"Topical Application of Doxycycline Inhibits Th2 Cell Development Mediated by Langerhans Cells and Exerts a Therapeutic Effect on Atopic Dermatitis","year":2020,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science","keywords":"Doxycycline; Immunoglobulin E; Atopic dermatitis; Immune system; Immunology; Medicine; Lymph; Langerhans cell; T helper cell; Ovalbumin; Antibody; T cell; Antibiotics; Biology; Pathology; Microbiology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008140397,0.0002675555,0.0003472826,0.0001949653,0.0001157745,0.0001454315,0.0001318231,0.0001997392,0.0009418614],"category_scores_gemma":[0.00007960723,0.00005101641,0.000132813,0.0001048999,0.0001622165,0.0001241014,0.0000956525,0.0004046454,0.0001590496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001516989,"about_ca_system_score_gemma":0.0001576583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003325815,"about_ca_topic_score_gemma":0.0006820019,"domain_scores_codex":[0.9999223,0.00001361957,0.000008231189,0.00001583495,0.00001620639,0.0000237772],"domain_scores_gemma":[0.9999379,0.00001135609,0.00001715397,0.000006996028,0.000007458549,0.0000191328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004171308,0.0002118242,0.0002069112,0.0001411659,0.00000736585,0.00005007427,0.00001058439,0.00006002623,0.9920013,0.00003198686,0.00009083246,0.00677094],"study_design_scores_gemma":[0.0001849936,0.003807045,0.007832764,0.00003488593,0.00005123788,0.0003839555,0.00002798777,0.0007735619,0.9821622,0.0000274151,0.004708164,0.000005720042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894812,0.007835424,0.0007293078,0.00009009439,0.00006466243,0.00006303521,0.0001501975,0.0000855837,0.001500507],"genre_scores_gemma":[0.995827,0.002205148,0.0007634508,0.00003356356,0.00003059963,0.0000454524,0.0001287219,0.00000881725,0.0009571861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009418614,"threshold_uncertainty_score":0.00315088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0339635960130413,"score_gpt":0.352068076190729,"score_spread":0.3181044801776877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}