{"id":"W3017952778","doi":"10.1111/all.14333","title":"Phenotype consensus is required to enable large‐scale genetic consortium studies of food allergy","year":2020,"lang":"en","type":"letter","venue":"Allergy","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of Waterloo; Allergan (Canada); McGill University Health Centre; AllerGen; Hospital for Sick Children; Université du Québec à Chicoutimi; University of Manitoba; Université Laval; BC Children's Hospital; Manitoba Health; University of Calgary; University of British Columbia; University of Toronto; Queen's University","funders":"Canadian Institutes of Health Research; Pfizer Canada","keywords":"Food allergy; Oral food challenge; Medicine; Population; Blinding; Genetic testing; Genome-wide association study; Gold standard (test); Clinical trial; Allergy; Immunology; Genetics; Biology; Pathology; Single-nucleotide polymorphism; Environmental health; Internal medicine; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001617223,0.0006825253,0.001714188,0.0004111485,0.0001762672,0.00002758301,0.0005366494,0.0007425318,0.001391435],"category_scores_gemma":[0.0004618262,0.0006249145,0.000477234,0.0006696327,0.0004234313,0.00003086708,0.0005274958,0.001428784,0.0004143596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001122698,"about_ca_system_score_gemma":0.0005889044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001098495,"about_ca_topic_score_gemma":0.0003862013,"domain_scores_codex":[0.995204,0.0002163896,0.0009999399,0.001144988,0.00122527,0.001209362],"domain_scores_gemma":[0.9970149,0.0003369721,0.0003011681,0.001107747,0.0008227541,0.0004164253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004616246,0.0001505271,0.00000994843,0.0008497012,0.005142354,0.001356542,0.001527198,0.00001184293,0.002325454,0.00007509149,0.9875739,0.0005158089],"study_design_scores_gemma":[0.001793468,0.003328162,0.00009761246,0.0004164897,0.00003892544,0.00004564047,0.0006385206,0.00004035252,0.004531875,0.0005176247,0.9879898,0.0005614877],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01458822,0.01905799,0.00002900075,0.9525408,0.0008676478,0.001111132,0.0004381851,0.0001889624,0.01117812],"genre_scores_gemma":[0.04377709,0.004711004,0.002166522,0.9159271,0.004727752,0.0001937267,0.0004970716,0.0003232926,0.02767643],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03661364,"threshold_uncertainty_score":0.9996202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05740685241856312,"score_gpt":0.3134217803913712,"score_spread":0.2560149279728081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}