{"id":"W3018071643","doi":"10.1136/lupus-2020-000383","title":"Acthar Gel (repository corticotropin injection) for persistently active SLE: study design and baseline characteristics from a multicentre, randomised, double-blind, placebo-controlled trial","year":2020,"lang":"en","type":"article","venue":"Lupus Science & Medicine","topic":"Adrenal Hormones and Disorders","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals","keywords":"Medicine; Placebo; Internal medicine; Double blind; Alternative medicine; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006735555,0.0003510903,0.00115438,0.000185214,0.0004567314,0.00006024055,0.0002272632,0.00009318552,0.00007391407],"category_scores_gemma":[0.002370012,0.0002414143,0.0001499158,0.00048799,0.0006272379,0.0002784743,0.00006100281,0.0002728293,0.000006076086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001248364,"about_ca_system_score_gemma":0.0004127927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001979778,"about_ca_topic_score_gemma":0.00001121836,"domain_scores_codex":[0.9968827,0.0001487566,0.0007911585,0.0008148836,0.0008801612,0.0004823081],"domain_scores_gemma":[0.9971848,0.0009299745,0.0003975341,0.0002920094,0.0004551625,0.0007404843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9766815,0.0006387162,0.001305614,0.00003305273,0.0002105708,0.00005348986,0.008685762,0.0000476657,0.00964099,0.000004349444,0.0003940573,0.002304289],"study_design_scores_gemma":[0.9226658,0.009343512,0.0006062086,0.00008150973,0.001693068,0.00004931039,0.01262638,0.05214089,0.00037061,0.000004418279,0.0001826135,0.0002356483],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9643369,0.0004738692,0.01517007,0.002430406,0.001899555,0.01546826,0.00001259218,0.00008274652,0.0001255502],"genre_scores_gemma":[0.995721,0.0000695576,0.0006584073,0.001038078,0.00135937,0.0006654119,0.00003937821,0.00002970964,0.0004191152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05401561,"threshold_uncertainty_score":0.9844589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0435476210145936,"score_gpt":0.3022930592605447,"score_spread":0.2587454382459511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}