{"id":"W3018071643","doi":"10.1136/lupus-2020-000383","title":"Acthar Gel (repository corticotropin injection) for persistently active SLE: study design and baseline characteristics from a multicentre, randomised, double-blind, placebo-controlled trial","year":2020,"lang":"en","type":"article","venue":"Lupus Science & Medicine","topic":"Adrenal Hormones and Disorders","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals","keywords":"Medicine; Placebo; Internal medicine; Double blind; Alternative medicine; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006458207,0.002019495,0.004295423,0.000615239,0.0005520689,0.001260689,0.0008963805,0.002218278,0.007971944],"category_scores_gemma":[0.004225012,0.0007036217,0.002425783,0.0007757106,0.0012272,0.00109399,0.0005699177,0.001477061,0.001103464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006015782,"about_ca_system_score_gemma":0.001538284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003459669,"about_ca_topic_score_gemma":0.0007247394,"domain_scores_codex":[0.9966862,0.002118869,0.0002534146,0.0004203077,0.000242625,0.0002786651],"domain_scores_gemma":[0.997957,0.0007074022,0.0005165631,0.0001718951,0.0001667818,0.0004803308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9812109,0.003650626,0.001139909,0.001192323,0.001248031,0.00005447486,0.00005085563,0.0001675593,0.001904543,0.00005605356,0.0003614714,0.008963204],"study_design_scores_gemma":[0.9336535,0.06225157,0.002431631,0.00004454808,0.0007926187,0.00003753257,0.00001343586,0.0001308722,0.0001395471,0.00005543506,0.0004364409,0.00001281488],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9491318,0.01666715,0.001549694,0.0008519856,0.0005470565,0.02627808,0.002530858,0.0001218423,0.002321528],"genre_scores_gemma":[0.9658602,0.004694127,0.002684615,0.001482329,0.0006915298,0.02066825,0.001933109,0.00002790828,0.001957923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007971944,"threshold_uncertainty_score":0.03415465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0435476210145936,"score_gpt":0.3022930592605447,"score_spread":0.2587454382459511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}