{"id":"W3018118152","doi":"10.3390/pharmaceutics12040389","title":"Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing","year":2020,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Providence Health Care Research Institute","funders":"Fogarty International Center; European Commission; National Health and Medical Research Council; Lung Foundation Australia; Rijksuniversiteit Groningen; U.S. Department of Veterans Affairs","keywords":"Senescence; Idiopathic pulmonary fibrosis; Wound healing; A549 cell; Lung; Cell growth; Cell biology; Fibroblast; Pathology; Biology; Immunology; Cancer research; Medicine; Cell culture; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001187634,0.0001212992,0.0002016558,0.00005071843,0.00004066826,0.00001728516,0.00004236698,0.00005917501,0.00001743943],"category_scores_gemma":[0.00003784148,0.0001169458,0.00005098014,0.000156559,0.00004426755,0.0001387048,0.0000347703,0.0001789059,0.000003111534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004072023,"about_ca_system_score_gemma":0.00008149262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002981923,"about_ca_topic_score_gemma":0.000005585872,"domain_scores_codex":[0.9990877,0.0000489638,0.0002960898,0.0002107189,0.0001900084,0.0001665169],"domain_scores_gemma":[0.9995727,0.00002017554,0.00008651304,0.00007837229,0.0000713769,0.0001708927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.003800289,0.0002815691,0.06551971,0.003117053,0.00002866929,0.00006020006,0.003920454,0.0002506119,0.920511,0.00005215174,0.0001133504,0.002344928],"study_design_scores_gemma":[0.002745286,0.001641511,0.00707633,0.0007537724,0.0002851047,0.00003489888,0.0002883088,0.5849931,0.3992865,0.00004539303,0.002557101,0.0002926354],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935799,0.001071347,0.001498566,0.002996725,0.00008586508,0.00060225,0.00004712798,0.00002653014,0.00009168017],"genre_scores_gemma":[0.9980926,0.0003305337,0.0005946624,0.0006837651,0.0002077553,0.000009591684,0.00004005502,0.00001603468,0.00002503389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5847425,"threshold_uncertainty_score":0.476891,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02389742866730687,"score_gpt":0.3063114509825321,"score_spread":0.2824140223152252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}