{"id":"W3018722345","doi":"10.1093/ofid/ofaa148","title":"Frailty Is Associated With Increased Hemagglutination-Inhibition Titers in a 4-Year Randomized Trial Comparing Standard- and High-Dose Influenza Vaccination","year":2020,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; McMaster University; Dalhousie University; Health Sciences North","funders":"National Institute on Aging; National Institutes of Health","keywords":"Medicine; Hemagglutination assay; Vaccination; Antibody titer; Titer; Influenza vaccine; Immunology; Antibody; Immunity; Randomized controlled trial; Influenza A virus; Virology; Virus; Internal medicine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004999938,0.001005739,0.002422675,0.0002933513,0.0004023878,0.000843389,0.0008250201,0.001574973,0.002751351],"category_scores_gemma":[0.005257986,0.0006328147,0.002387883,0.0003075557,0.001039868,0.0006835978,0.0005459397,0.001592566,0.0002455096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006400531,"about_ca_system_score_gemma":0.00113085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001233521,"about_ca_topic_score_gemma":0.001682223,"domain_scores_codex":[0.9978021,0.001379965,0.0002067963,0.0002937321,0.0001085885,0.0002087976],"domain_scores_gemma":[0.995653,0.001630749,0.001243931,0.0003967501,0.0002347857,0.0008407935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9878664,0.002310361,0.003241275,0.0002496142,0.001658915,0.0000128482,0.00002430401,0.0001592227,0.000794689,0.00002231506,0.0001380791,0.003521904],"study_design_scores_gemma":[0.787934,0.1790045,0.02665773,0.0001087656,0.003776831,0.00003934205,0.00003841024,0.001095979,0.0008617516,0.0001524667,0.0003025584,0.00002766924],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972953,0.001535804,0.0001564477,0.0001545646,0.0001608053,0.0003252861,0.0001434239,0.00001262454,0.0002156914],"genre_scores_gemma":[0.9982305,0.0003728286,0.0003471083,0.0001602923,0.0001089681,0.0003640233,0.000170453,0.000002605613,0.0002431953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004999938,"threshold_uncertainty_score":0.02644253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04769427872990162,"score_gpt":0.3462271977959114,"score_spread":0.2985329190660098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}