{"id":"W3018818368","doi":"10.3390/cancers12051076","title":"Tumor-Infiltrating CD8 T Cells Predict Clinical Breast Cancer Outcomes in Young Women","year":2020,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"","keywords":"Breast cancer; Immune system; Tumor-infiltrating lymphocytes; CD8; Young adult; Medicine; Oncology; Cancer; Transcriptome; Internal medicine; Physiology; Immunology; Biology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003015098,0.0002057892,0.0005529231,0.00005547995,0.00004748988,0.00002335546,0.0001482808,0.00009172215,0.001070912],"category_scores_gemma":[0.00004879525,0.0001745611,0.000173514,0.0003516173,0.0001533807,0.0000994516,0.00003169887,0.0003691435,0.00001825494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001702942,"about_ca_system_score_gemma":0.001211056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002080784,"about_ca_topic_score_gemma":0.0004142422,"domain_scores_codex":[0.9982191,0.00005701317,0.0005964937,0.0004081148,0.0002672761,0.0004519896],"domain_scores_gemma":[0.9992109,0.0000722269,0.000150273,0.0002151763,0.00004617081,0.0003052541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002714847,0.00003583517,0.9672678,0.0001354397,0.0002707305,0.00007787939,0.002163964,0.0001255336,0.01007111,0.000003545609,0.005745114,0.01138823],"study_design_scores_gemma":[0.008775931,0.000575301,0.9738956,0.0003297195,0.00007346553,0.00003998978,0.002362252,0.001747401,0.00185157,0.000006113617,0.009929849,0.0004128235],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920456,0.0004531808,0.00001276439,0.004021433,0.0009282868,0.0004284937,0.0001280159,0.00009251217,0.00188969],"genre_scores_gemma":[0.9895454,0.0005084425,0.00008783539,0.008728651,0.0006106556,0.0001195586,0.000006233137,0.00003523839,0.0003579861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0109754,"threshold_uncertainty_score":0.9998422,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02856968692251706,"score_gpt":0.3208290709741268,"score_spread":0.2922593840516097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}