{"id":"W3018981957","doi":"10.1186/s13223-020-00419-z","title":"Protocol for a double-blind, randomized controlled trial on the dose-related efficacy of omalizumab in multi-food oral immunotherapy","year":2020,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institut Universitaire en Santé Mentale de Québec; Hospital for Sick Children; SickKids Foundation; University of Toronto; Centre Hospitalier de l’Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research; Novartis Pharmaceuticals Canada","keywords":"Omalizumab; Dosing; Medicine; Placebo; Dose; Oral immunotherapy; Maintenance dose; Randomized controlled trial; Allergy; Surgery; Food allergy; Internal medicine; Immunology; Immunoglobulin E; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0427319,0.009010613,0.01223115,0.003148774,0.00573295,0.003852032,0.003941575,0.01054576,0.08916233],"category_scores_gemma":[0.04171578,0.004198798,0.005006727,0.003683838,0.004953974,0.003725172,0.001884492,0.01513505,0.01919495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005015826,"about_ca_system_score_gemma":0.01779107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001851186,"about_ca_topic_score_gemma":0.00434301,"domain_scores_codex":[0.9595507,0.02448233,0.003784283,0.003332546,0.005449473,0.003400604],"domain_scores_gemma":[0.9724586,0.00776468,0.005207417,0.004088223,0.006904548,0.003576557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9223933,0.01441077,0.0005122342,0.01029435,0.001440793,0.0002030152,0.0002788578,0.001254068,0.002543076,0.005511594,0.01917468,0.02198323],"study_design_scores_gemma":[0.9455661,0.02067385,0.001092696,0.001392227,0.0004848461,0.00004660943,0.00005083637,0.001697397,0.0008171575,0.001884464,0.02620584,0.00008818612],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.001133304,0.0001660565,0.001221033,0.0001429281,0.0006640909,0.9951575,0.0006443625,0.0001120774,0.0007585118],"genre_scores_gemma":[0.001814213,0.00008257422,0.001930473,0.0002147568,0.00009439333,0.9953309,0.0001106461,0.000007244227,0.000414786],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.08916233,"threshold_uncertainty_score":0.2982777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1281026521262575,"score_gpt":0.4266244699684372,"score_spread":0.2985218178421797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}