{"id":"W3019193608","doi":"10.3390/cancers12041021","title":"STAT5 is Expressed in CD34+/CD38− Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms","year":2020,"lang":"en","type":"article","venue":"Cancers","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Oesterreichische Nationalbank; Austrian Science Fund","keywords":"Cancer research; Stem cell; STAT5; CD38; Biology; Essential thrombocythemia; Janus kinase 2; Flow cytometry; CD34; Molecular biology; Chemistry; Polycythemia vera; Signal transduction; Immunology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006890656,0.000184547,0.0001111671,0.0003282915,0.0001179166,0.000173609,0.00009545542,0.0001566192,0.001714624],"category_scores_gemma":[0.00007615736,0.00007674299,0.0001269142,0.0001922011,0.0001499615,0.0001377752,0.0001081214,0.0002102839,0.000304173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001900308,"about_ca_system_score_gemma":0.0001011518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003259972,"about_ca_topic_score_gemma":0.0003208282,"domain_scores_codex":[0.9999315,0.00000907204,0.00000639847,0.00001322123,0.00002326304,0.00001651019],"domain_scores_gemma":[0.9999682,0.000004662742,0.000009060934,0.00000273451,0.000003447118,0.00001196111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000191288,0.00002027566,0.00212887,0.00005358272,0.000004134248,0.0001366215,0.00001361547,0.00006177234,0.9941161,0.00009351911,0.00004818411,0.003132069],"study_design_scores_gemma":[0.00004598115,0.0008585327,0.07741269,0.00001789308,0.00005147886,0.003420504,0.00005882861,0.002016612,0.9108342,0.0002333354,0.00504403,0.000006074749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946477,0.002617431,0.001101297,0.00005188102,0.00001002066,0.00001756409,0.0003453169,0.00004373522,0.001165046],"genre_scores_gemma":[0.9974195,0.0006251344,0.00075919,0.00002582574,0.000007469944,0.000009626237,0.0005413566,0.000003118593,0.0006087245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001714624,"threshold_uncertainty_score":0.005735993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0140913861476569,"score_gpt":0.2532661724250303,"score_spread":0.2391747862773734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}