{"id":"W3019283745","doi":"10.1016/j.bbrc.2020.04.056","title":"Nuclear localization of ING3 is required to suppress melanoma cell migration, invasion and angiogenesis","year":2020,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research; Health Commission of Zhejiang Province; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"NLS; Nuclear localization sequence; Nuclear transport; Cytoplasm; Cell biology; Chemistry; Nuclear protein; Biology; Transcription factor; Cell nucleus; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009765352,0.00008483623,0.0001088411,0.00003866542,0.0001591058,0.00002915782,0.0002676398,0.0001126045,0.00001402593],"category_scores_gemma":[0.0001744085,0.00007600595,0.00003907974,0.0002739437,0.0002869009,0.000007629841,0.0005282377,0.0000986918,0.000007986391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005988461,"about_ca_system_score_gemma":0.00002135156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004575161,"about_ca_topic_score_gemma":0.000004174901,"domain_scores_codex":[0.9991758,0.00009515784,0.0001530375,0.0002642805,0.0001733097,0.0001383893],"domain_scores_gemma":[0.9991015,0.00003927634,0.00003257726,0.0004330429,0.0002025124,0.0001910704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001066478,0.00005688284,0.0002673892,0.00003718214,0.00001149408,1.038044e-7,0.0002952881,4.772444e-7,0.9886259,0.0002681255,0.008903523,0.001427015],"study_design_scores_gemma":[0.0002148422,0.000483412,0.001095986,0.00001287,0.00001406726,0.000001028582,0.0001974133,0.001151985,0.9514855,0.0001178909,0.04511271,0.0001123256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917465,0.0005695481,0.0002535596,0.006859586,0.000008398197,0.0001898175,0.00003663745,0.00001016186,0.0003258053],"genre_scores_gemma":[0.9971305,0.000807544,0.001250782,0.0005785252,0.0000771523,0.000008954959,0.0001070659,0.0000131078,0.0000264207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0371404,"threshold_uncertainty_score":0.3099433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04760433370535173,"score_gpt":0.3046152941089023,"score_spread":0.2570109604035506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}