{"id":"W3019435489","doi":"10.1016/j.cels.2020.03.003","title":"BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain","year":2020,"lang":"en","type":"article","venue":"Cell Systems","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Regina; University of Toronto","funders":"National Institute on Aging; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; ALS Society of Canada; National Human Genome Research Institute; Boston University; BrightFocus Foundation; National Institutes of Health; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Alzheimer's Association","keywords":"Interactome; Neuroscience; Computational biology; Biology; Amyotrophic lateral sclerosis; RNA splicing; Brain function; Function (biology); Cell biology; RNA; Disease; Genetics; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001759985,0.000319067,0.0002214196,0.001288185,0.0003129919,0.0008661778,0.0003135504,0.0003041186,0.003839905],"category_scores_gemma":[0.0009147775,0.0001711094,0.0002201512,0.001140094,0.0003462421,0.001516193,0.0005046918,0.0004787039,0.000562211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002686685,"about_ca_system_score_gemma":0.0004191831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001724072,"about_ca_topic_score_gemma":0.003173119,"domain_scores_codex":[0.9999549,0.000009964719,0.000001386914,0.00001468983,0.00001199767,0.000006912036],"domain_scores_gemma":[0.9997956,0.00009139114,0.00003685478,0.00002470828,0.00002831381,0.00002316537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004592484,0.00009060705,0.02994691,0.001043255,0.0004060413,0.0008380354,0.001100218,0.05111459,0.4245943,0.1529892,0.01809581,0.3193219],"study_design_scores_gemma":[0.0000559395,0.0002599049,0.1697894,0.0001730472,0.0003025971,0.002121798,0.0007790276,0.2388043,0.05893463,0.4507194,0.07793009,0.0001297577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.664849,0.00749234,0.2886508,0.003547552,0.0001442337,0.00004200318,0.00725462,0.002834558,0.02518486],"genre_scores_gemma":[0.9361685,0.00395242,0.05330522,0.0001989238,0.0001266491,0.00005964602,0.002935681,0.0004496772,0.002803332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003839905,"threshold_uncertainty_score":0.01284575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02483734540395343,"score_gpt":0.2570001698161456,"score_spread":0.2321628244121922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}