{"id":"W3019934757","doi":"10.1371/journal.pgen.1008750","title":"ArdC, a ssDNA-binding protein with a metalloprotease domain, overpasses the recipient hsdRMS restriction system broadening conjugation host range","year":2020,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España; University of British Columbia; Ministerio de Educación, Cultura y Deporte","keywords":"Plasmid; Pseudomonas putida; Biology; Escherichia coli; Bacterial conjugation; Metalloproteinase; Cell biology; Function (biology); DNA; Genetics; Bacteria; Gene; Matrix metalloproteinase","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000141997,0.0002783658,0.0002376154,0.00004848184,0.0002189856,0.0001025629,0.0003297782,0.0003030779,0.000007824327],"category_scores_gemma":[0.00007022978,0.0001999555,0.00008529297,0.0002833517,0.0001327141,0.000005260916,0.0001939564,0.0002202666,0.00001728069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004158388,"about_ca_system_score_gemma":0.00009783046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000608208,"about_ca_topic_score_gemma":0.0000175954,"domain_scores_codex":[0.9983404,0.0001295589,0.0003344644,0.0005490956,0.0002940356,0.0003523916],"domain_scores_gemma":[0.9990056,0.000009372412,0.0002507507,0.0004533005,0.000145761,0.0001352793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002931907,0.0000466005,0.0005413819,0.00008039687,0.0001424829,0.00001092007,0.00009181282,0.00003957683,0.9983168,0.0001861679,0.000117281,0.0001333372],"study_design_scores_gemma":[0.0009199054,0.001267099,0.0003669498,0.00008827098,0.0001235768,0.00002518715,0.000411102,0.0003906423,0.9821706,0.00001683058,0.01387902,0.0003408398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943111,0.0004551901,0.001627452,0.001919924,0.0001141207,0.001244368,0.00005721946,0.00007111643,0.0001995368],"genre_scores_gemma":[0.9956693,0.0001928302,0.003016411,0.0002473378,0.0004851301,0.0002036541,0.00008188999,0.00005272038,0.00005071583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01614627,"threshold_uncertainty_score":0.8153946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01511433560342624,"score_gpt":0.2019694456738905,"score_spread":0.1868551100704642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}