{"id":"W3019966488","doi":"10.18203/2349-3259.ijct20201718","title":"Autologous chondrocyte transplantation: a phase 1 study protocol to validate the safety and feasibility of a new advanced cell therapy product for articular cartilage repair in Brazil","year":2020,"lang":"en","type":"article","venue":"International Journal of Clinical Trials","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sociedade Beneficente Israelita Brasileira Albert Einstein","keywords":"Medicine; Chondrocyte; Transplantation; Cartilage; Surgery; Fibrin glue; Osteoarthritis; Pathology; Anatomy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004809367,0.0001176763,0.0009021924,0.00005638637,0.00002134524,0.00001330364,0.0001389192,0.00004014726,0.00003572484],"category_scores_gemma":[0.003998225,0.00006946954,0.000401633,0.00009269489,0.00003463181,0.00009907744,0.00001603026,0.0001615204,0.000001066913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002309297,"about_ca_system_score_gemma":0.0002863139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003101599,"about_ca_topic_score_gemma":0.000008233555,"domain_scores_codex":[0.9963495,0.0006093145,0.002304975,0.0002304218,0.0004050456,0.0001007619],"domain_scores_gemma":[0.9974401,0.001079038,0.0008096864,0.0001321253,0.0003463625,0.0001926828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6102204,0.007775337,0.01957344,0.0001497447,0.0006974627,0.0008854332,0.00572286,0.0001375675,0.09579084,0.00005508889,0.0005308667,0.2584609],"study_design_scores_gemma":[0.5028851,0.09231513,0.01763819,0.0005899458,0.0007924433,0.0002548706,0.0007522388,0.0001356827,0.363953,0.0008333732,0.01956145,0.0002886483],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.936231,0.00008311634,0.001028309,0.008665225,0.0003168387,0.05359768,0.00004917434,0.00001152484,0.00001717827],"genre_scores_gemma":[0.9928465,0.00008219309,0.003617206,0.0008507145,0.0006916695,0.001837791,0.000004844711,0.00001241855,0.00005668375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2681621,"threshold_uncertainty_score":0.4786537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2565776535820389,"score_gpt":0.5460777100973343,"score_spread":0.2895000565152954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}