{"id":"W3020008008","doi":"10.1177/0960327120918307","title":"A review of neuropsychiatric adverse events from topical ophthalmic brimonidine","year":2020,"lang":"en","type":"review","venue":"Human & Experimental Toxicology","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"","keywords":"Brimonidine; Medicine; Clonidine; Vigilance (psychology); Adverse effect; Glaucoma; Topical medication; Intraocular pressure; Anesthesia; Ophthalmology; Pharmacology; Psychology; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005094055,0.0009418125,0.001496221,0.00419161,0.0003696127,0.0009124876,0.0008622044,0.0007257723,0.005083205],"category_scores_gemma":[0.001291691,0.0002991882,0.0009988758,0.004076368,0.0002862225,0.001010054,0.0005609753,0.0008685498,0.0009434511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005365187,"about_ca_system_score_gemma":0.001392287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001737679,"about_ca_topic_score_gemma":0.003480716,"domain_scores_codex":[0.9996662,0.00005829866,0.0001075745,0.00005219721,0.000098004,0.0000177324],"domain_scores_gemma":[0.9992853,0.0003839841,0.00015795,0.00001392004,0.000126528,0.00003234547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00009771027,0.00007065028,0.0004477726,0.1490452,0.0003573675,0.0005759798,0.0001851741,0.0002984151,0.0009743442,0.001095965,0.03668568,0.8101657],"study_design_scores_gemma":[0.00004296315,0.0002419437,0.004845858,0.06353993,0.001398062,0.008399413,0.0002182105,0.0001196573,0.0005373981,0.001420495,0.9191831,0.00005301954],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001392575,0.9991289,0.00004038801,0.00009790107,0.0001010453,0.000006033872,0.00003122003,0.000004957585,0.0004502893],"genre_scores_gemma":[0.000504884,0.999042,0.00008224809,0.0000955864,0.00008017152,0.000005558089,0.0000323182,8.273055e-7,0.0001563002],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005083205,"threshold_uncertainty_score":0.01700503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05300670457407631,"score_gpt":0.3877082370592366,"score_spread":0.3347015324851603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}