{"id":"W3020203132","doi":"10.1101/2020.04.22.20072389","title":"SARS-CoV-2 On-the-Spot Virus Detection Directly from Patients","year":2020,"lang":"en","type":"preprint","venue":"medRxiv","topic":"SARS-CoV-2 detection and testing","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Technion-Israel Institute of Technology; Canadian Institute for Advanced Research","keywords":"Reverse Transcription Loop-mediated Isothermal Amplification; Loop-mediated isothermal amplification; Protocol (science); Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Population; Saliva; Pandemic; Medicine; Coronavirus disease 2019 (COVID-19); Computer science; Reverse transcriptase; Biology; RNA; Pathology; Environmental health; Internal medicine; DNA; Genetics; Gene; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"high","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001006895,0.0008480678,0.0005820176,0.0004965778,0.0002368167,0.0005770221,0.0003947984,0.0009232298,0.002275907],"category_scores_gemma":[0.001266581,0.0003079714,0.0005008677,0.0002213512,0.0003610904,0.000270889,0.0004640739,0.0007530108,0.0014077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001618276,"about_ca_system_score_gemma":0.0002360482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004882279,"about_ca_topic_score_gemma":0.0005351696,"domain_scores_codex":[0.9984416,0.0005848017,0.0000844222,0.0002966338,0.0004598405,0.0001327337],"domain_scores_gemma":[0.9994435,0.0002069846,0.00005859029,0.00008007366,0.0001750617,0.00003578391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004064753,0.0001519787,0.009641785,0.0003051266,0.00005107918,0.0001742059,0.0002399318,0.0002180549,0.975807,0.00007300012,0.0007438752,0.01218753],"study_design_scores_gemma":[0.00001869447,0.0008940757,0.01499524,0.00003107891,0.00008363399,0.0006718976,0.0001473195,0.002598658,0.9771738,0.0001245121,0.003235453,0.00002571833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9335707,0.001927052,0.05399087,0.0003515081,0.000416777,0.0009020969,0.002944454,0.0009386811,0.00495782],"genre_scores_gemma":[0.9396837,0.0008159189,0.04999871,0.0005942829,0.0001290539,0.000460953,0.002879554,0.000151084,0.005286756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002275907,"threshold_uncertainty_score":0.007613719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07675458335087908,"score_gpt":0.3020125803530285,"score_spread":0.2252579970021494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}