{"id":"W3020273460","doi":"10.3390/cancers12051078","title":"Clinical Variables Associated with PSA Response to Lutetium-177-PSMA ([177Lu]-PSMA-617) Radionuclide Treatment in Men with Metastatic Castration-Resistant Prostate Cancer","year":2020,"lang":"en","type":"article","venue":"Cancers","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Prostate cancer; Univariate analysis; Oncology; Logistic regression; Internal medicine; Radionuclide therapy; Prostate; Urology; Prostate-specific antigen; Statistical significance; Cancer; Multivariate analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005671075,0.0001683855,0.0003429683,0.0006273755,0.0002592947,0.0003790156,0.0002361662,0.0004646316,0.0007289585],"category_scores_gemma":[0.002408322,0.0001584104,0.0003173847,0.0007719921,0.0003223889,0.0003316803,0.0002130508,0.0004096034,0.0001606634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002198481,"about_ca_system_score_gemma":0.0002587913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001138508,"about_ca_topic_score_gemma":0.001480507,"domain_scores_codex":[0.9996637,0.0001294491,0.00004162261,0.00005411863,0.00006156816,0.00004951412],"domain_scores_gemma":[0.9983853,0.0006908835,0.0005421749,0.00005515105,0.00009239595,0.000234235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003612145,0.00003567591,0.9981084,0.000007506708,0.00001964621,0.0001079929,0.00002386615,0.00009519166,0.0002908387,0.000008288773,0.00003579969,0.0009055958],"study_design_scores_gemma":[0.00001826372,0.000376326,0.9984595,0.000003265378,0.00002245298,0.0004225665,0.00007453607,0.000378385,0.0001099281,0.00001639645,0.0001148711,0.000003559435],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992761,0.0003957191,0.00004688092,0.00002771488,0.00000385755,0.000006176752,0.00007938382,0.000001990235,0.0001622359],"genre_scores_gemma":[0.9997404,0.00006036653,0.00003072557,0.00001221069,0.000009280534,0.000005210636,0.00009248529,6.77617e-7,0.00004857517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001138508,"threshold_uncertainty_score":0.002999187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06131948215227576,"score_gpt":0.3671668196228092,"score_spread":0.3058473374705334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}