{"id":"W3020669081","doi":"10.1016/j.bpj.2020.04.012","title":"Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly","year":2020,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Heparin-Induced Thrombocytopenia and Thrombosis","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Folding (DSP implementation); Heparin; Platelet factor 4; Platelet; Chemistry; Biophysics; Protein folding; Biochemistry; Biology; Immunology; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002104811,0.0004511364,0.0002099175,0.0001294359,0.0005942822,0.0005395732,0.0003250089,0.0004345367,0.002021372],"category_scores_gemma":[0.0004673966,0.0002473873,0.0003237314,0.0001447522,0.0003015113,0.0007014885,0.0002749111,0.0006054637,0.000470113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004607203,"about_ca_system_score_gemma":0.0002486491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007995638,"about_ca_topic_score_gemma":0.0008359465,"domain_scores_codex":[0.9998593,0.00003965745,0.000009142847,0.00002534364,0.00002221586,0.00004425413],"domain_scores_gemma":[0.9998351,0.00004812327,0.00004173417,0.00001187358,0.00002141759,0.00004166604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005685313,0.0001712452,0.003659387,0.0001264497,0.00006457197,0.0009066041,0.0003450326,0.002476082,0.9805067,0.005057977,0.0007437426,0.005373803],"study_design_scores_gemma":[0.0001072224,0.001003513,0.02602648,0.00008111565,0.000148267,0.001530743,0.000697619,0.03990069,0.9130688,0.007538293,0.009824032,0.00007322711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917411,0.001393341,0.004001327,0.0004772197,0.00005999537,0.00001336694,0.00005509997,0.00004057764,0.002218153],"genre_scores_gemma":[0.9968323,0.0004635746,0.001237659,0.0001920839,0.00001683769,0.00001073239,0.0001353472,0.00001383394,0.001097599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002021372,"threshold_uncertainty_score":0.006762147,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08406244783154715,"score_gpt":0.3422949985789289,"score_spread":0.2582325507473817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}