{"id":"W3020841146","doi":"10.1021/acsomega.0c00207","title":"Promising Performance of 4HMS, a New Zirconium-89 Octadendate Chelator","year":2020,"lang":"en","type":"article","venue":"ACS Omega","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Université de Sherbrooke","keywords":"Chelation; Biodistribution; Chemistry; In vivo; Transmetalation; Zirconium; Radiochemistry; Positron emission tomography; Bifunctional; Clearance; Nuclear chemistry; Combinatorial chemistry; In vitro; Nuclear medicine; Inorganic chemistry; Organic chemistry; Biochemistry; Catalysis; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003853292,0.000305718,0.0002900513,0.0001777039,0.0001383671,0.0004338018,0.0004188348,0.0004432706,0.001672546],"category_scores_gemma":[0.0001846371,0.0001247285,0.0002268789,0.0001396779,0.0001628198,0.000299031,0.0002301982,0.0001868894,0.001017568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002805414,"about_ca_system_score_gemma":0.0002870992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000744102,"about_ca_topic_score_gemma":0.001044167,"domain_scores_codex":[0.9998628,0.00002448517,0.000007047559,0.00002587358,0.00004934982,0.00003051241],"domain_scores_gemma":[0.9999381,0.000009989862,0.00001381516,0.000008419819,0.00001874007,0.0000108909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005275497,0.00001815984,0.0002100232,0.0001520532,0.0000129751,0.00003805857,0.00001845671,0.0001663023,0.987398,0.000271826,0.0007275364,0.01045898],"study_design_scores_gemma":[0.00003016983,0.0005031773,0.0008338185,0.000006749683,0.0000269604,0.00009801892,0.00001406482,0.0006291826,0.9847289,0.00003808997,0.01308369,0.000007171624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9406211,0.02537548,0.01447321,0.0009052707,0.0004367181,0.0001168077,0.001074402,0.001460153,0.0155368],"genre_scores_gemma":[0.9660155,0.004177666,0.01312479,0.0002624842,0.00008076557,0.00004126604,0.0011159,0.00008726963,0.01509441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001672546,"threshold_uncertainty_score":0.005595207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05150747890076066,"score_gpt":0.3079633295413438,"score_spread":0.2564558506405831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}