{"id":"W3020892681","doi":"10.1080/07391102.2013.786524","title":"90 Intra-accumbens injection of a dopamine aptamer abates MK-801-induced cognitive dysfunction in a model of Schizophrenia","year":2013,"lang":"en","type":"article","venue":"Journal of Biomolecular Structure and Dynamics","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Aptamer; Nucleus accumbens; NMDA receptor; Dopamine; Oligonucleotide; Pharmacology; Chemistry; Neuroscience; Biophysics; DNA; Biology; Receptor; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001124661,0.0001625187,0.0003201035,0.0002315397,0.00002406461,0.00001332246,0.00007563381,0.0002086019,0.000001558037],"category_scores_gemma":[0.00008755599,0.0001300043,0.0001254868,0.0002181659,0.0001096787,0.00001774689,0.00004353618,0.0001580672,5.151734e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002166333,"about_ca_system_score_gemma":0.00005803212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005114228,"about_ca_topic_score_gemma":0.00008556433,"domain_scores_codex":[0.9990036,0.00004983309,0.0004851284,0.000174573,0.0001550056,0.000131818],"domain_scores_gemma":[0.9988526,0.00001065649,0.0005232642,0.000124798,0.0004343353,0.0000543083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002724066,0.00004765156,0.000960113,0.00002734261,0.0001222806,0.000002826965,0.00003022869,0.0002226971,0.980791,0.00002606021,0.000006835423,0.01749056],"study_design_scores_gemma":[0.001004244,0.000983657,0.001946166,0.0000978747,0.0001163897,0.000183265,0.0002243671,0.02757039,0.9665861,0.001110561,0.000002907859,0.0001741129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9333862,0.0001954688,0.06617955,0.00003932825,0.00004099838,0.000108457,0.00002732855,0.000003478511,0.00001918048],"genre_scores_gemma":[0.9927826,0.0001796384,0.006885829,0.00004081419,0.0000456793,0.000001026136,0.00004016627,0.00001429339,0.000009983833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05939636,"threshold_uncertainty_score":0.5301419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005523646601918441,"score_gpt":0.2399806773509108,"score_spread":0.2344570307489923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}