{"id":"W3021024502","doi":"10.1182/blood.2019003646","title":"Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Phagocytosis; Antibody; In vitro; In vivo; Immunology; Polyclonal antibodies; Platelet; Monoclonal antibody; Immune system; Antigen; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004831002,0.0004119641,0.0004428795,0.0003514408,0.0001322745,0.0002549349,0.0002459586,0.0005041598,0.0007631275],"category_scores_gemma":[0.0003772504,0.0001644705,0.0002365137,0.0001690356,0.0001502247,0.0001878961,0.0001475336,0.0009180544,0.0001942083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000199118,"about_ca_system_score_gemma":0.0001242742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004749188,"about_ca_topic_score_gemma":0.0006254113,"domain_scores_codex":[0.9995074,0.0002697162,0.00003704471,0.00003106841,0.00008253508,0.00007216579],"domain_scores_gemma":[0.9995816,0.0001870908,0.00008297813,0.00005868983,0.00005610835,0.00003355575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002759813,0.0002939397,0.001151931,0.00006507405,0.00001432324,0.00006035598,0.00002927816,0.0002183025,0.9947349,0.0001360029,0.00004276216,0.002977189],"study_design_scores_gemma":[0.00002583054,0.002542772,0.005288162,0.000007511619,0.0000360294,0.0002210017,0.0000137081,0.001813511,0.9893864,0.0000354625,0.0006261169,0.000003536576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876519,0.003117684,0.006427263,0.00008546386,0.00003852283,0.00007620395,0.0001328034,0.00008493702,0.002385093],"genre_scores_gemma":[0.9946468,0.0007126043,0.003335017,0.00005776597,0.00002398923,0.00005559708,0.0002198429,0.00001231869,0.0009360345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007631275,"threshold_uncertainty_score":0.002554893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01755044565006638,"score_gpt":0.2654066695713415,"score_spread":0.2478562239212751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}