{"id":"W3021032174","doi":"10.1016/j.cell.2020.04.009","title":"Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production","year":2020,"lang":"en","type":"article","venue":"Cell","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":246,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Technische Universität Dresden; Boehringer Ingelheim Fonds; Max-Planck-Gesellschaft; Volkswagen Foundation; European Research Council; Human Frontier Science Program","keywords":"Biology; Translation (biology); Protein biosynthesis; Housekeeping gene; Ribosome profiling; Cell biology; Heat shock protein; Heat shock; Messenger RNA; Gene; Gene expression; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003241876,0.0006180851,0.0004187977,0.0003151802,0.0004791874,0.0005129089,0.0003378287,0.0004248307,0.002749764],"category_scores_gemma":[0.000373809,0.0003252845,0.0004259199,0.00025882,0.0004395343,0.000416884,0.0007184661,0.0008861746,0.001042261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008155521,"about_ca_system_score_gemma":0.0002793273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003967667,"about_ca_topic_score_gemma":0.0007531655,"domain_scores_codex":[0.9997681,0.00003686853,0.00001797076,0.00008115901,0.00004717892,0.0000487248],"domain_scores_gemma":[0.9995078,0.0001615213,0.00008263039,0.00009465097,0.000058775,0.00009478303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001084096,0.00001131019,0.0001888932,0.00002713785,0.0000050106,0.0001279675,0.00001725176,0.00005107639,0.9985217,0.0002536869,0.00008981112,0.0005977823],"study_design_scores_gemma":[0.000005870016,0.00002435838,0.001370331,0.000001398918,0.000002939006,0.0001016825,0.00001388533,0.0002426428,0.9968001,0.00006151421,0.001372572,0.000002700121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770511,0.001405735,0.01648332,0.0004262931,0.0002243208,0.00005864114,0.0009626919,0.000347789,0.003040112],"genre_scores_gemma":[0.9883677,0.000275114,0.004345118,0.0001855071,0.00007472203,0.0000368791,0.00166903,0.0002802283,0.004765656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002749764,"threshold_uncertainty_score":0.009198904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01969345718576838,"score_gpt":0.2488678165740912,"score_spread":0.2291743593883228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}