{"id":"W3021053184","doi":"10.1002/mds.28052","title":"Microbiota Composition and Metabolism Are Associated With Gut Function in Parkinson's Disease","year":2020,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":319,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Sport Centre Pacific; University of British Columbia Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Parkinson Canada","keywords":"Gut flora; Parkinson's disease; Constipation; Feces; Biology; Physiology; Disease; Gastrointestinal function; Gut–brain axis; Medicine; Internal medicine; Irritable bowel syndrome; Gastroenterology; Immunology; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004691667,0.0001167935,0.0001087208,0.00002526921,0.00005832508,0.00001851024,0.00004632454,0.00005346911,0.00001183232],"category_scores_gemma":[0.000009340816,0.0001101569,0.00002617788,0.00008621516,0.00003563799,0.000004341437,0.00003821894,0.00006196382,0.000002004332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001510185,"about_ca_system_score_gemma":0.00002773514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000350648,"about_ca_topic_score_gemma":0.0003919078,"domain_scores_codex":[0.9993404,0.00004265082,0.0001101371,0.0002775596,0.00005644086,0.0001727843],"domain_scores_gemma":[0.9997224,0.000002753415,0.00006560953,0.00008850804,0.00001824468,0.0001024821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005135227,0.0002270775,0.2157634,0.00005663545,0.00007186287,0.000002974573,0.0001181768,0.0001193109,0.777209,0.00005622203,0.005245238,0.0006165328],"study_design_scores_gemma":[0.001711373,0.0001452312,0.9794571,0.00002846441,0.00003510216,4.907829e-8,0.000175062,0.00007533706,0.001361249,0.0001129797,0.01671039,0.0001876961],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993395,0.001029365,0.000330575,0.004812217,0.00003528442,0.0002666484,0.00005253396,0.00001216159,0.00006620743],"genre_scores_gemma":[0.9890043,0.0003036428,0.00003733247,0.01018463,0.00002939473,0.00001578263,0.0003748486,0.00001417464,0.00003593995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7758478,"threshold_uncertainty_score":0.4492068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006126205596244045,"score_gpt":0.2011858797749254,"score_spread":0.1950596741786814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}