{"id":"W3021129457","doi":"10.1111/trf.15779","title":"Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion","year":2020,"lang":"en","type":"review","venue":"Transfusion","topic":"Blood transfusion and management","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Tufts University School of Medicine; Deutsches Rote Kreuz; University of Texas Medical School at Houston; Johns Hopkins University; University of Washington; Washington University in St. Louis; Beth Israel Deaconess Medical Center","keywords":"Clinical trial; Medicine; Platelet; Intensive care medicine; Clinical endpoint; Platelet transfusion; Surrogate endpoint; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002222119,0.0008828615,0.003773302,0.0003931844,0.0004450096,0.00006898911,0.0002452175,0.0005501458,0.000136619],"category_scores_gemma":[0.000173126,0.0005484436,0.00071427,0.0007256588,0.00006648689,0.0001124411,0.00007216975,0.0007914699,0.00001379737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009650353,"about_ca_system_score_gemma":0.0003104233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005399133,"about_ca_topic_score_gemma":0.00001277161,"domain_scores_codex":[0.9947494,0.001333818,0.001360701,0.001501033,0.0004542138,0.0006007896],"domain_scores_gemma":[0.9978612,0.0007972913,0.0002364058,0.0005859021,0.00008233469,0.0004368619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006661566,0.0004419454,0.000001621516,0.01986994,0.0005321033,0.0002060596,0.001433364,9.908741e-7,0.0008687487,0.00007198851,0.000250639,0.9756564],"study_design_scores_gemma":[0.005419665,0.002308398,0.00001001801,0.01198668,0.009953288,0.0002927017,0.0008776484,0.00007820289,0.00006589782,0.00007285338,0.9682578,0.0006768468],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008334733,0.8544339,0.1219791,0.001397395,0.0003260138,0.02127199,0.00008785283,0.0002532669,0.0001671285],"genre_scores_gemma":[0.0000326547,0.9692864,0.02772791,0.000206216,0.0003567843,0.001525342,0.0002118797,0.0002016383,0.0004511693],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9749796,"threshold_uncertainty_score":0.9996967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2137720721515409,"score_gpt":0.4013721884089702,"score_spread":0.1876001162574293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}