{"id":"W3021211843","doi":"10.1016/b978-0-08-046884-6.00425-5","title":"Uptake Transporters","year":2010,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Transporter; Efflux; Solute carrier family; Organic anion transporter 1; Organic cation transport proteins; Membrane transport protein; Biochemistry; Chemistry; Xenobiotic; Biology; Zwitterion; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001977881,0.001985329,0.001369465,0.001343333,0.0008136363,0.00302124,0.001070568,0.002045881,0.09650648],"category_scores_gemma":[0.0002488747,0.0006431168,0.0006419417,0.001926787,0.0005589632,0.003060977,0.001430368,0.002309755,0.1238666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001012952,"about_ca_system_score_gemma":0.0008080162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001455935,"about_ca_topic_score_gemma":0.001867488,"domain_scores_codex":[0.9998124,0.0000115429,0.00001000075,0.00005275383,0.00009123923,0.00002200821],"domain_scores_gemma":[0.9999274,0.00001417624,0.000006358964,0.00001295772,0.00002912825,0.0000100538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001016152,0.00009528834,0.0001330552,0.001277307,0.0000228123,0.0005028907,0.0002402337,0.0005605007,0.07696459,0.06200867,0.1878973,0.6701957],"study_design_scores_gemma":[0.000006942352,0.00002274515,0.0001289974,0.0001285026,0.00001070508,0.0005183718,0.00004234463,0.0002926663,0.008376972,0.006639945,0.9838214,0.00001051389],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.003377926,0.08696546,0.03052058,0.003493959,0.002696925,0.0001173111,0.001853873,0.002795483,0.8681784],"genre_scores_gemma":[0.004853574,0.02671614,0.004861873,0.0007298191,0.0001915002,0.00006821284,0.001257817,0.0002569888,0.9610642],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.09650648,"threshold_uncertainty_score":0.3228464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01236411936622449,"score_gpt":0.2276564069128875,"score_spread":0.215292287546663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}