{"id":"W3021222597","doi":"10.1152/ajpendo.00093.2020","title":"Reducing 14-3-3ζ expression influences adipocyte maturity and impairs function","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Canada Foundation for Innovation; Canada Research Chairs; Government of Canada","keywords":"Adipocyte; Lipolysis; Adipose triglyceride lipase; Perilipin; Adipogenesis; Hormone-sensitive lipase; Lipid droplet; Biology; Adipose tissue; Endocrinology; Internal medicine; Lipase; Peroxisome; Catabolism; Biochemistry; Chemistry; Cell biology; Receptor; Enzyme; Metabolism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001572712,0.0003985592,0.0003107399,0.0002116707,0.0002209632,0.0004369496,0.0002354447,0.0002725415,0.001037407],"category_scores_gemma":[0.0001293755,0.0001593064,0.0003876119,0.0002161934,0.0003147397,0.0002238091,0.0003044321,0.0007274145,0.0003448849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004464262,"about_ca_system_score_gemma":0.0004363277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001519392,"about_ca_topic_score_gemma":0.001750343,"domain_scores_codex":[0.9998167,0.00001363929,0.00002064864,0.00004832151,0.00004832483,0.00005240121],"domain_scores_gemma":[0.999871,0.00001404247,0.00003563246,0.00001772486,0.00001892375,0.00004256488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001255507,0.00001859244,0.0003222939,0.00001540993,0.000003589928,0.00001344343,0.000008419056,0.00004350158,0.9987572,0.00006651202,0.000009685544,0.0006157017],"study_design_scores_gemma":[0.00001233305,0.0001827013,0.006091499,0.000004891453,0.0000229104,0.00005917955,0.00003055698,0.0006490358,0.9911252,0.00008899702,0.001727877,0.000004785329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942411,0.001398476,0.002938084,0.0001008712,0.00005535859,0.00002474342,0.0003864089,0.00008053343,0.000774402],"genre_scores_gemma":[0.9942895,0.001154334,0.001571557,0.00007784026,0.000008923515,0.0000233462,0.0004790857,0.0000429481,0.002352428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001519392,"threshold_uncertainty_score":0.00347054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008505773492217782,"score_gpt":0.2503152369082861,"score_spread":0.2418094634160683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}